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Nanocellulose is not only a biocompatible and environmentally friendly material but also has excellent mechanical properties, biodegradability, and a large number of hydroxyl groups that have a strong affinity for water. These characteristics have attracted significant attention from researchers in the field of glucose sensing.
This review provides a brief overview of the current research status of traditional materials used in glucose sensors. The sensing performance, chemical stability, and environmental properties of nanocellulose-based glucose sensors are compared and summarized based on the three sensing methods: electrochemical sensing, colorimetric sensing, and fluorescence sensing. The article focuses on recent strategies for glucose sensing using nanocellulose as a matrix. The development prospects of nanocellulose-based glucose sensors are also discussed.
Nanocellulose has outstanding structural characteristics that contribute significantly to the sensing performance of glucose sensors in different detection modes. However, the preparation process for high-quality nanocellulose is complicated and has a low yield. Furthermore, the sensitivity and selectivity of nanocellulose-based glucose sensors require further improvement.
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