The Vitamin D Neuroendocrine System as a Target for Novel Neurotropic Drugs

A. V. Kalueff; A. Minasyan; T. Keisala; M. Kuuslahti; S. Miettinen; P. Tuohimaa

doi:10.2174/187152706784111506

ISSN: 1871-5273
E-ISSN: 1996-3181

The Vitamin D Neuroendocrine System as a Target for Novel Neurotropic Drugs
Authors: A. V. Kalueff¹, A. Minasyan², T. Keisala³, M. Kuuslahti⁴, S. Miettinen⁵ and P. Tuohimaa⁶
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¹ Department of Anatomy, Medical School, University of Tampere, Tampere 33014, Finland. ² Department of Anatomy, Medical School, University of Tampere, Tampere 33014, Finland. ³ Department of Anatomy, Medical School, University of Tampere, Tampere 33014, Finland. ⁴ Department of Anatomy, Medical School, University of Tampere, Tampere 33014, Finland. ⁵ Department of Anatomy, Medical School, University of Tampere, Tampere 33014, Finland. ⁶ Department of Anatomy, Medical School, University of Tampere, Tampere 33014, Finland.
Source: CNS & Neurological Disorders - Drug Targets (Formerly Current Drug Targets - CNS & Neurological Disorders), Volume 5, Issue 3, Jun 2006, p. 363 - 371
DOI: https://doi.org/10.2174/187152706784111506
- Available online: 01 Jun 2006

Abstract

Vitamin D is a seco-steroid hormone with multiple functions in the nervous system. Physiological brain mechanisms of vitamin D and its receptors include neuroprotection, antiepileptic effects, immunomodulation, possible interplay with several brain neurotransmitter systems and hormones, as well as the regulation of behaviours. Here we review the important role of the vitamin D neuroendocrine system in the brain, and outline perspectives for the search for novel neurotropic drugs to treat various vitamin D-related dysfunctions.

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2006-06-01

2025-09-19

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Article Type: Research Article

Keyword(s): brain disorders; neurosteroid hormone; new drugs; Vitamin D

The Vitamin D Neuroendocrine System as a Target for Novel Neurotropic Drugs

Abstract

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