Skip to content
2000
Volume 8, Issue 2
  • ISSN: 2405-4615
  • E-ISSN: 2405-4623

Abstract

Introduction: Zinc oxide nanoparticles belong to the new age of nanomaterials; they are being used tremendously for the advancements of biomedicine and modern therapeutic interventions. Purpose: The current antimicrobial treatment methods fail on various levels. Thus, the recent study is dedicated to synthesizing stable zinc oxide nanoparticles. Therefore, the application of zinc oxide nanoparticles as an alternative treatment option is explored. Methods: In the current research, fabrication of zinc oxide nanoparticles is carried out via the wet chemical method. To further confirm the purity and stability of the synthesized material, characterization was performed via zeta potential analysis, thermogravimetric analysis, differential scanning calorimetry, transmission electron microscopy and scanning electron microscopy. Results: SEM and TEM revealed the spherical structure of zinc oxide nanoparticles, also having slight agglomeration at a few points. The thermal stability was tested via thermogravimetric analysis and differential Scanning Calorimetry depicting the strength of the nanomaterial at a very high temperature. Elemental composition was evaluated using Energy Dispersive X-ray Spectroscopy showing 96.01% zinc and 3.99% oxygen, demonstrating the purity of the synthesized zinc oxide nanoparticles. It confirms that no other elements are present apart from zinc and oxygen. Conclusion: Zinc oxide nanoparticles were synthesized via a wet chemical method using zinc nitrate and sodium hydroxide. This fabrication procedure is reliable, cheap, and yields the most stable byproducts. Characterization was carried out via several analytical techniques to check the authenticity of the synthesized nanomaterial, thus revealing that the obtained ZnO nanoparticles could be used in medical interventions as a safe option.

© Bentham Science Publishers
Loading

Article metrics loading...

/content/journals/cnm/10.2174/2405461507666220603115619
2023-08-01
2026-03-09

  • From This Site

    /content/journals/cnm/10.2174/2405461507666220603115619
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

References

  1. Tiller J.C. Liao C.J. Lewis K. Klibanov A.M. Designing surfaces that kill bacteria on contact. Proc. Natl. Acad. Sci. 2001 98 11 5981 5985 10.1073/pnas.111143098 11353851
    [Google Scholar]
  2. Thill A. Zeyons O. Spalla O. Cytotoxicity of CeO2 nanoparticles on Escherichia Coli: Physiochemical insight of cytotoxicity mechanism. Environ. Sci. Technol. 2006 40 6151 10.1021/es060999b 17051814
    [Google Scholar]
  3. Jones N. Ray B. Ranjit K.T. Manna A.C. Antibacterial activity of ZnO nanoparticle suspensions on a broad spectrum of microorganisms. FEMS Microbiol. Lett. 2008 279 1 71 76 10.1111/j.1574‑6968.2007.01012.x 18081843
    [Google Scholar]
  4. Brayner R. Ferrari-Iliou R. Brivois N. Djediat S. Benedetti M.F. Fiévet F. Toxicological impact studies based on Escherichia coli bacteria in ultrafine ZnO nanoparticles colloidal medium. Nano Lett. 2006 6 4 866 870 10.1021/nl052326h 16608300
    [Google Scholar]
  5. Desselberger U. Emerging and re-emerging infectious diseases. J. Infect. 2000 40 1 3 15 10.1053/jinf.1999.0624 10762105
    [Google Scholar]
  6. Morones J.R. Elechiguerra J.L. Camacho A. The bactericidal effect of silver nanoparticles. Nanotechnology 2005 16 10 2346 2353 10.1088/0957‑4484/16/10/059 20818017
    [Google Scholar]
  7. Sawai J. Quantitative evaluation of antibacterial activities of metallic oxide powders (ZnO, MgO and CaO) by conductimetric assay. J. Microbiol. Methods 2003 54 2 177 182 10.1016/S0167‑7012(03)00037‑X 12782373
    [Google Scholar]
  8. Seil J.T. Webster T.J. Antimicrobial applications of nanotechnology: Methods and literature. Int. J. Nanomed 2012 7 2767 2781 22745541
    [Google Scholar]
  9. Ramani M. Ponnusamy S. Muthamizhchelvan C. From zinc oxide to micro flowers: A study of Growth kinetics and biocidal activity. Mater. Sci. Eng. C 2012 32 8 2381 2389 10.1016/j.msec.2012.07.011
    [Google Scholar]
  10. Kim K.M. Kim T.H. Kim H.M. Colloidal behaviors of ZnO nanoparticles in various aqueous media. Toxicol. Environ. Health Sci. 2012 4 2 121 131 10.1007/s13530‑012‑0126‑5
    [Google Scholar]
  11. Kim K.M. Choi M.H. Lee J.K. Physicochemical properties of surface charge-modified ZnO nanoparticles with different particle sizes. Int. J. Nanomed 2014 9 2 Suppl. 2 41 56 25565825
    [Google Scholar]
  12. Kumar H. Rani R. Structural and optical characterization of ZnO nanoparticles synthesized by microemulsion route. Int Lett Chem Phys Astron 2013 14 26 36
    [Google Scholar]
/content/journals/cnm/10.2174/2405461507666220603115619
Loading

  • Article Type:     Research Article
Keyword(s): differential scanning calorimetry; energy dispersive X-ray spectroscopy; nanotechnology; transmission electron microscopy; wet chemical method; ZnO nanoparticles

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test