PET-MRI Based Molecular Imaging as a Response Marker in Cervical Cancer: A Systematic Review

Therapeutic strategies continue to evolve for treatment of women with cervical cancer. However there is dearth of validated biomarkers of therapeutic response and overall survival. In recent years development of molecular imaging techniques using Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) has allowed evaluation of imaging biomarkers of proliferation, angiogenesis, perfusion and hypoxia as prognostic imaging biomarkers. The present systematic review summarizes the current role of multifunctional PET and MRI as a response biomarker for cervical cancer.