Preface [Hot topic: Treatment of Human Immunodeficiency Virus (HIV) Infection and Co-Pathologies (Guest Editor: Andreas Gruber)]

In this issue experts in the field highlight recent advances in our understanding of HIV, the AIDS virus. The current issue will give an overview also of how the rapidly evolving knowledge about HIV may lead the way to new therapies not only for HIV but also for other diseases such as cancer, genetic deficiencies, autoimmune diseases and fungal infections. Much progress has been made; however, a cure for HIV has not yet been found and seems to be a goal hard to reach. Till a cure for HIV is found, the major goal is, besides preventing new infections, to increase life expectancy and quality of individuals already infected with HIV. New and improved drug- and immune-based therapies with increased efficacy and fewer side effects may be part of this solution. Not all side effects of current anti-HIV drugs are harmful. This issue will also summarize how some of the side effects of these drugs may even open new avenues into the treatment of cancer, autoimmune diseases and fungal infections. I wish you an insightful reading and thank the contributors very much.