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- ISSN: 1568-0150
- E-ISSN: 1875-6158
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Non Peptidic CCK-2 (Formerly CCK-B) Antagonists: A Five Years Overview
- Source: Current Medicinal Chemistry - Central Nervous System Agents, Volume 2, Issue 4, Dec 2002, p. 287 - 294
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- 01 Dec 2002
Abstract
Cholecystokinin (CCK) receptors are divided into CCK-1 (formerly CCK-A) and CCK-2 (formerly CCK-B) sub-types. CCK is a widely distributed neuropeptide in the brain and is considered a central nervous system transmitter. Possible therapeutic applications for CCK-2 antagonists include panic, anxiety, analgesia, schizophrenia, gastric disorders, and gastrointestinal tumours. This review covers the last five years findings in the field of such molecules
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