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2000
Volume 9, Issue 7
  • ISSN: 1570-162X
  • E-ISSN: 1873-4251

Abstract

CD4C/HIVNef Tg mice express HIV-1 Nef in relevant target cells through the regulatory sequences of the human CD4 gene. These mice develop a severe disease showing many characteristics of human AIDS. A summary of the results obtained with these Tg mice is presented.

© Bentham Science Publishers
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/content/journals/chr/10.2174/157016211798842062
2011-10-01
2025-09-05

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  • Article Type:     Research Article
Keyword(s): AIDS; AIDS-LIKE DISEASE; CD4C/HIVNef; HIV-1; HIVAN; mouse model; Nef; SIV; Tg DC; Transgene

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