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2000
  • ISSN: 1568-010X
  • E-ISSN: 1568-010X

Abstract

There is a growing body of evidence that oxidative stress mediated by reactive oxygen species plays an important role in the pathogenesis of various kinds of allergic and non-allergic inflammation. These data suggest that blocking reactive oxygen species should be useful for amelioration of allergic or non-allergic inflammation in the respiratory and intestinal tracts. In addition, the modulation of oxidative stress-related molecules, such as inducible nitric oxide synthase and redox-sensitive transcriptional factors, may be useful for the regulation of these inflammatory responses. In this review, we have summarized the recent advances in the prevention of allergic or non-allergic inflammation, especially the diesel exhaust particle-induced respiratory allergic response and dextran sulfate sodium-induced intestinal inflammation in rodents.

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/content/journals/cdtia/10.2174/1568010054526269
2005-08-01
2025-09-18
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/content/journals/cdtia/10.2174/1568010054526269
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  • Article Type:
    Review Article
Keyword(s): antioxidant; inducible nitric oxide synthase; nuclear factor; oxidative stress
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