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- ISSN: 1389-4501
- E-ISSN: 1873-5592
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Future Targets in Endothelial Biology: Endothelial Cell to Mesenchymal Transition
- Source: Current Drug Targets, Volume 17, Issue 15, Dec 2016, p. 1707 - 1713
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- 01 Dec 2016
Abstract
Endothelial to mesenchymal transition (EndMT) is a poorly understood phenomenon that results in normal endothelial cells acquiring a mesenchymal phenotype. EndMT has been observed in a number of pathological conditions, from cancer to fibrosis to cardiovascular disease and the process itself may play an important mechanistic role in the development of these disease states.
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