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- ISSN: 1389-4501
- E-ISSN: 1873-5592
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Advances in Hyaluronic Acid-Based Drug Delivery Systems
- Source: Current Drug Targets, Volume 17, Issue 6, May 2016, p. 720 - 730
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- 01 May 2016
Abstract
Hyaluronic acid (HA) is a relatively new polymer for the construction of drug delivery systems. CD44 and the receptor for HA-mediated motility play a key role in vivo for the receptormediated endocytosis of HA. Cellular uptake and the efficiency of tumor-targeted drug delivery are supposed to increase through utilizing HA as drug carriers. Currently, HA has provided a promising platform to physically encapsulate or chemically conjugate with various drugs. In this review, we presented the most latest advances in HA-based drug delivery systems and some forward-looking ideas are discussed.
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