Full text loading...
- ISSN: 1389-4501
- E-ISSN: 1873-5592
-
The Potential for Targeting Oncogenic WNT/β -Catenin Signaling in Therapy
- Source: Current Drug Targets, Volume 9, Issue 7, Jul 2008, p. 532 - 547
-
- 01 Jul 2008
Abstract
There has been a surge of interest in the therapeutic targeting of the Wnt pathway following the demonstration that it is activated in a wide variety of tumors and that blocking aberrant signaling promoted tumor cell apoptosis or differentiation. This review describes recent therapeutic approaches and discusses potential opportunities for intervention at multiple levels within the Wnt pathway.
© Bentham Science Publishers