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image of Nanostructured Systems for Effective Transdermal Drug Delivery

Abstract

Introduction

One of the least invasive, recognized potential routes for both local and systemic drug delivery and the most patient-friendly methods of administering therapeutic agents is transdermal drug delivery. It minimizes gastrointestinal side effects, prevents hepatic first-pass metabolism, lowers dosage frequency, and boosts patient compliance.

Objective

This review aims to examine the nanostructured systems for transdermal drug delivery, focusing on their types, design, development and mechanism in enhancing drug permeation through the skin.

Methods

This review article synthesized findings from recent studies on nanostructured systems used in transdermal drug delivery systems. With a particular focus on offering a comprehensive understanding of transdermal drug delivery methods and augmentation strategies, the author examines current trends and potential uses of transdermal technologies.

Results

Nanostructured systems have shown increased drug penetration, improved bioavailability and controlled release profiles.

Conclusion

Nanostructured systems offer a versatile and effective approach to overcoming the limitations of traditional transdermal drug delivery methods. Future research should focus on optimizing these systems for clinical applications, ensuring safety and regulatory compliance.

© 2025 Bentham Science Publishers
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2025-08-04
2025-08-13

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/content/journals/cdd/10.2174/0115672018355526250311045617
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Nanostructured Systems for Effective Transdermal Drug Delivery
Bentham Science Publishers ; https://doi.org/10.2174/0115672018355526250311045617
/content/journals/cdd/10.2174/0115672018355526250311045617
/content/journals/cdd/10.2174/0115672018355526250311045617
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  • Article Type:     Research Article
Keywords: metallic nanoparticles ; nanosystems ; niosomes ; microneedles ; Transdermal ; dendrimers ; liposomes ; ethosomes

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