A Review of the Computational Methods for Identifying the Over- Annotated Genes and Missing Genes in Microbial Genomes

Jia-Feng Yu; Zhen-Zhen Guo; Xiao Sun; Ji-Hua Wang

doi:10.2174/1574893608999140109120612

ISSN: 1574-8936
E-ISSN: 2212-392X

A Review of the Computational Methods for Identifying the Over- Annotated Genes and Missing Genes in Microbial Genomes
By Jia-Feng Yu, Zhen-Zhen Guo, Xiao Sun and Ji-Hua Wang
Source: Current Bioinformatics, Volume 9, Issue 2, Apr 2014, p. 147 - 154
DOI: https://doi.org/10.2174/1574893608999140109120612
- Available online: 01 Apr 2014

Abstract

More and more studies indicate that the issue of protein-coding gene finding in microbial genomes is far from thoroughly solved and the annotation quality has been questioned continuously in the past several years. In this paper, we summarize the computational methods for identifying the over-annotated genes and missing genes, and provide perspective for prospective gene finding works.

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2014-04-01

2025-09-04

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Article Type: Research Article

Keyword(s): Microbial genome; missing gene; over-annotated gene; protein-coding gene; re-annotation

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A Review of the Computational Methods for Identifying the Over- Annotated Genes and Missing Genes in Microbial Genomes

Abstract

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