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Microbial electrosynthesis (MES), a process that uses electricity as energy source for driving the production of chemicals and fuels using microorganisms and CO2 or organics as carbon sources, has recently gained attention as a biosustainable strategy for the production of bio-methane due to its efficiency and versatility. In this review the scientific context, the challenges and some casestudies of microbial electrosynthesis of methane are briefly discussed.