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2000
Volume 24, Issue 1
  • ISSN: 2211-3525
  • E-ISSN: 2211-3533

Abstract

Introduction/Objective

The cost of an antibiotic may significantly increase personal expenses, which affects a country's total gross domestic product (GDP). The percentage of lost GDP per person of the Iraqi population due to the cost of antibiotics was studied.

Methods

A prescriptive study was conducted to assess the cost of common prescription antibiotics in Iraq based on data obtained from 32 pharmacies in four Iraqi governorates. The cost of antibiotics based on the total GDP of patients was determined as a percentage.

Results and Discussion

The specialization of physicians and the type and form of antibiotics were the effective factors associated with the impact of the cost of antibiotics on the GDP per person in Iraq. A high percentage of GDP per person was reduced by the cost of antibiotics prescribed by pediatricians and otolaryngologists (ENT) (64.18% and 56.19%, respectively). Cefpodoxime and ciprofloxacin were the costliest types of antibiotics with greater GDP reduction. Based on the form, syrups and tablets were the most expensive antibiotics. Amoxicillin had forms costing between 27.02% and 77.69% of the total GDP per patient, while chloramphenicol had only one form, drops.

Conclusion

The cost of antibiotics has a major impact on the overall GDP of the population of Iraq. This effect is significantly influenced by the specialization of physicians, and the type and the form of antibiotic. Restricting the prescription of unnecessary antibiotics and expensive types is highly recommended to lower the cost and burden on the GDP of Iraqis.

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References

  1. KleinE.Y. Van BoeckelT.P. MartinezE.M. PantS. GandraS. LevinS.A. GoossensH. LaxminarayanR. Global increase and geographic convergence in antibiotic consumption between 2000 and 2015.Proc. Natl. Acad. Sci. USA201811515E3463E347010.1073/pnas.1717295115 29581252
    [Google Scholar]
  2. NandiA. PecettaS. BloomD.E. Global antibiotic use during the COVID-19 pandemic: Analysis of pharmaceutical sales data from 71 countries, 2020–2022.E. Clin. Med.20235710184810.1016/j.eclinm.2023.101848 36776504
    [Google Scholar]
  3. KleinE.Y. ImpalliI. PoleonS. DenoelP. CiprianoM. Van BoeckelT.P. PecettaS. BloomD.E. NandiA. Global trends in antibiotic consumption during 2016–2023 and future projections through 2030.Proc. Natl. Acad. Sci. USA202412149e241191912110.1073/pnas.2411919121 39556760
    [Google Scholar]
  4. MarahZ.A.A. AbdulkareemA.A. GulS.S. AlshamiM.L. A survey of systemic antibiotic prescription patterns amongst Iraqi dentists.Int. Dent. J.202272333834510.1016/j.identj.2021.06.002 34344542
    [Google Scholar]
  5. AL-TukmagiHF. Self-medication towards antibiotic use among non-medical university staff.Iraqi J. Pharm Sci.202231917
    [Google Scholar]
  6. MohammedS.S. ShlashA.M.J. A study of self-medication uses without a prescription among Iraqi patients in Baghdad city.Indian J. Forensic Med. Toxicol.20211524587459210.37506/ijfmt.v15i2.15109
    [Google Scholar]
  7. SalimK.S. HasanE.K. NumanI.T. Prevalence of antibiotic use among medical students in Iraq.Sys. Rev. Pharm.202112512515
    [Google Scholar]
  8. SalimK.S. AlsabahA.S. TaghiH.S. Misuse of antibiotics in Iraq: A review of Iraqi published studies. Al-Mustansiriyah.J. Pharm. Sci.2022212152010.32947/ajps.v21i2.805
    [Google Scholar]
  9. MarasineN.R. ShresthaS. SankhiS. PaudelN. GautamA. PoudelA. Antibiotic utilization, sensitivity, and cost in the medical intensive care unit of a tertiary care teaching hospital in Nepal.SAGE. Open. Med.202192050312121104371010.1177/20503121211043710 34504707
    [Google Scholar]
  10. ZilberbergM.D. NathansonB.H. SulhamK. FanW. ShorrA.F. 30-day readmission, antibiotics costs and costs of delay to adequate treatment of Enterobacteriaceae UTI, pneumonia, and sepsis: A retrospective cohort study.Antimicrob. Resist. Infect. Control20176112410.1186/s13756‑017‑0286‑9 29225798
    [Google Scholar]
  11. SilvaM.L. CargnelloC. Aulois-GriotM. DumartinC. Antibiotic misuse: How to evaluate the costs?Med. Mal. Infect.201949748549410.1016/j.medmal.2019.03.012 30954321
    [Google Scholar]
  12. OgawaV.A. TranT.A. MundacaS. Understanding the economics of microbial threats: Proceedings of a workshop. National Academies of Sciences, Engineering, and MedicineThe National Academies PressWashington, DC201810.17226/25224
    [Google Scholar]
  13. DoN.T.T. VuH.T.L. NguyenC.T.K. PunpuingS. KhanW.A. GyapongM. Community-based antibiotic access and use in six low-income and middle-income countries: A mixed-method approach.Lancet Glob. Health20219e610e61910.1016/S2214‑109X(21)00024‑3
    [Google Scholar]
  14. MallahN. OrsiniN. FigueirasA. TakkoucheB. Income level and antibiotic misuse: A systematic review and dose–response meta-analysis.Eur. J. Health Econ.20222361015103510.1007/s10198‑021‑01416‑8 34845563
    [Google Scholar]
  15. DadgostarP. Antimicrobial resistance: Implications and costs.Infect. Drug Resist.2019123903391010.2147/IDR.S234610 31908502
    [Google Scholar]
  16. EgglestonK. ZhangR. ZeckhauserR.J. The global challenge of antimicrobial resistance: insights from economic analysis.Int. J. Environ. Res. Public Health2010783141314910.3390/ijerph7083141 20948953
    [Google Scholar]
  17. TaylorJ. HafnerM. YerushalmiE. SmithR. BellasioJ. VardavasR. Bienkowska-GibbsT. RubinJ. Estimating the economic costs of antimicrobial resistance, model and results.2014Available from: https://www.rand.org/pubs/research_reports/RR911.html
  18. CharanJ. BiswasT. How to calculate sample size for different study designs in medical research?Indian J. Psychol. Med.201335212112610.4103/0253‑7176.116232 24049221
    [Google Scholar]
  19. GDP per capita (current US$)-Iraq. 1960-2021. World Bank2021Available from: https://data.worldbank.org/indicator/NY.GDP.PCAP.CD?locations=IQ
  20. InanD. SabaR. GunserenF. OngutG. TurhanO. YalcinA.N. MamikogluL. Daily antibiotic cost of nosocomial infections in a Turkish university hospital.BMC Infect. Dis.200551510.1186/1471‑2334‑5‑5 15679899
    [Google Scholar]
  21. OmranS.T. Mohammed-JawadN.K. FareedN.Y. Population knowledge about rational use of antibiotics and antibiotics resistance in Basrah, Iraq.Res. J. Pharm. Technol.2021146659666410.52711/0974‑360X.2021.01150
    [Google Scholar]
  22. AL-NaseriMSA. Antibiotic misuse: Trends & attitude among Iraqi physicians. Kufa. J. Nursing.Sci.2019919
    [Google Scholar]
  23. KrivoyN. Abed El-AhalW. Bar-LavieY. HaddadS. Antibiotic prescription and cost patterns in a general intensive care unit.Pharm. Pract.200752677310.4321/S1886‑36552007000200003 25214920
    [Google Scholar]
  24. FranklinM. WailooA. DayerM.J. JonesS. PrendergastB. BaddourL.M. LockhartP.B. ThornhillM.H. The cost-effectiveness of antibiotic prophylaxis for patients at risk of infective endocarditis.Circulation2016134201568157810.1161/CIRCULATIONAHA.116.022047 27840334
    [Google Scholar]
  25. SinurayaR.K. AiniA.N. RahayuC. WathoniN. AbdulahR. The effectiveness of postoperative antibiotics following appendectomy in pediatric patients: A cost minimization analysis.Open Public Health J.2020131808610.2174/1874944502013010080
    [Google Scholar]
  26. JayanthiM. MeenaD.K. Cost analysis of different antibiotic brands available in indian market with reference to National List of Essential Medicines.Indian J. Community Med.2021461939610.4103/ijcm.IJCM_296_20 34035585
    [Google Scholar]
  27. HoriK.S. SiuA.M. YamamotoL.G. Replacing liquid antibiotics with cheaper pill equivalents: An opportunity for substantial savings.Clin. Pediatr.201857111294129910.1177/0009922818774340 29732920
    [Google Scholar]
  28. OppongR. SmithR.D. LittleP. VerheijT. ButlerC.C. GoossensH. CoenenS. MooreM. CoastJ. Cost effectiveness of amoxicillin for lower respiratory tract infections in primary care: An economic evaluation accounting for the cost of antimicrobial resistance.Br. J. Gen. Pract.201666650e633e63910.3399/bjgp16X686533 27402969
    [Google Scholar]
  29. MarraF. MarraC.A. PatrickD.M. Cost effectiveness analysis of azithromycin and doxycycline for Chlamydia trachomatis infection in women: A Canadian perspective.Can. J. Infect. Dis.199784202208 22346517
    [Google Scholar]
  30. SmithD. BuhimschiC. FinneranM. Cost analysis of azithromycin versus erythromycin in pregnancies complicated by preterm premature rupture of membranes.Am. J. Perinatol.201936110511010.1055/s‑0038‑1667369 30103220
    [Google Scholar]
  31. GauthamM. MillerR. RegoS. GoodmanC. Availability prices and affordability of antibiotics stocked by informal providers in rural India: A cross-sectional survey.Antibiotics202211452310.3390/antibiotics11040523 35453278
    [Google Scholar]
  32. AlzubaidiM.A. AlnajjarA.I. MahmoodA.K. KhairyA.S. AbdelzaherH.G. Towards good health and well-being; Antibiotic misuse in the general population.Egyptian J. Health Care2024151088110010.21608/ejhc.2024.362521
    [Google Scholar]
  33. Control antibiotic misuse or the drugs won’t work, warn WHO experts World Health Organization, Regional Office for Europe2023Available from: https://turkmenistan.un.org/en/253576-control-antibiotic-misuse-or-drugs-won%E2%80%99t-work-warn-who-experts
  34. IslamM.W. ShahjahanM. AzadA.K. HossainM.J. Factors contributing to antibiotic misuse among parents of school-going children in Dhaka City, Bangladesh.Sci. Rep.2024141231810.1038/s41598‑024‑52313‑y 38282010
    [Google Scholar]
  35. HossainM.A. SiamM.H.B. ImranA. LimonM.B.H. ZahidM.H. HossainM.A. SiddiqueM.A. SultanaM. Antibiotic abuse: A cross-sectional study on knowledge, attitude, and behavior among the University students in Dhaka, Bangladesh.Electron. J. Gen. Med.2021183em28910.29333/ejgm/10836
    [Google Scholar]
  36. Bu-KhamsinA.Y. FabellaE. Al AbdullahA.H. AlbatherM.R. Al-HassanY.T. AlramadanH.A. Al MoweshyA.A. Al AbdullahA.J. Al HassanH.I. Association between awareness on antibiotic resistance and antibiotic misuse among Saudi University students.Open Public Health J.202114154555410.2174/1874944502114010545
    [Google Scholar]
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