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Biosynthesis of Bacterial Nanocellulose

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Bacterial nanocellulose (BNC) biosynthesis is a well-organized and strictly controlled process and has two stages: first, the formation of 1,4-glucan linkages, and subsequently the assembly and cellulose crystallization. The process starts with the carbon source, such as glucose and fructose, being transported into the cell, where the cellulose precursor UDPG is produced. Bcs then polymerizes glucose from UDPG into 1,4-glucan strands. Finally, cellulose chains are secreted as sub-fibrils through pores in the cell membrane and then combined into ribbons in a 3D nanofiber network supported by hydrogen bonds.

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