Bioceramics and Bioactive Glasses for Skin Wound Healing

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This chapter provides an overview of wounds, distinguishing between acute and chronic types. It describes the dynamic process of wound healing, involving hemostasis, inflammation, proliferation, and maturation. The role of growth factors and cytokines in the healing process is highlighted, along with the importance of the extracellular matrix. The text emphasizes that chronic wounds, often associated with diseases like diabetes, tumors, or ischemia, have a higher likelihood of recurrence and a prolonged healing period. Additionally, factors such as infections, stress, age, hormonal issues, and medications can compromise the natural wound healing process. The current market offerings for wound dressings, such as gauze and films, often fall short in promoting effective wound healing due to various limitations. In contrast, specific types of bioceramics and bioactive glasses have shown potential for co-delivering therapeutic ions, presenting a smart approach to accelerate the wound healing process. The study emphasizes the need to explore and develop materials with therapeutic efficacy, moving beyond mere wound coverage to actively promoting healing and tissue regeneration.