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Applications of Advanced Nanocarriers in the Theranostics of Melanoma Skin Cancer

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Among the various types of skin cancer, melanoma is the most aggressive one, and the occurrences are rising rapidly throughout the universe. The early diagnosis rate of melanoma skin cancer is around 14-15%, which hasa survival rate of less than 5 years. Conventional medicines are unable to treat it completely, resulting in the destruction of healthy cells. Similarly, radiotherapy and chemotherapy have limitations of higher toxicity, multi-drug resistance, and minimal survival rates even after the treatment. The lipid-based nanoparticles are highly effective in the therapy of melanoma skin cancer only after the prompt diagnosis. The current book chapter signifies the applications of the advanced nanocarriers utilized for the diagnosis and therapy of skin cancer. These advanced nanocarriers are classified as polymer-based approaches (micelle, dendrimer, and hydrogels) and offer additional benefits like targeted action, controlled delivery, longer circulation time, and high loading efficiency. Nanoparticle-based approaches (organic and inorganic nanoparticles) and carbon-based approaches (nanotubes, graphene oxide) are widely utilized for possessing biosensing and diagnostic properties.

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