Glycyrrhiza glabra L. (Fabaceae)

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Glycyrrhiza glabra L. (Fabaceae), Page 1 of 1

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Glycyrrhiza glabra L., commonly known as licorice, is a prominent medicinal plant of the Fabaceae family, recognised for its extensive therapeutic applications in various traditional systems of medicine. Licorice, including the roots and rhizomes of Glycyrrhiza spp., is known not only for its pharmacological properties but also for its use in cosmetics as a depigmentation agent and in foods as a flavouring and sweetener. Glycyrrhiza glabra is one of the main representatives of the drug "licorice," whose main chemical constituents are triterpene saponins, flavonoids, and phenolic compounds. Licorice is cultivated throughout the world and is used in both conventional and traditional medicine. <br><br>The rhizomes and roots of licorice are used medicinally, either alone or in combination with other herbs, to treat a variety of conditions including stomach ulcers, hyperdipsia, flatulence, and colic, aside from respiratory conditions such as coughs, asthma, tonsillitis, and sore throats. Despite its long tradition and broad use, licorice is not without risk. A substantial number of side effects have been reported, predominantly with long-term use. Chronic or excessive use can lead to serious side effects, including hypokalemia, hypertension, and, in extreme cases, fatal cardiac events. This chapter also presents case reports that exemplify these adverse effects and highlight the importance of the cautious use of licorice in clinical practice. The findings suggest that while Glycyrrhiza glabra remains a valuable medicinal resource, its potential for toxicity requires careful administration and monitoring.