The Role of Dietary Agents in Preventing the Pathogenesis by Helicobacter pylori

- Authors: Rashmi T. D'souza1, Vijaya Marakala2, Rhea K. D'souza3, Mamatha Jayandran4, Pankaj Prabhakar5, Princy L. Palatty6, Manjeshwar Shrinath Baliga7
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View Affiliations Hide Affiliations1 Nitte University Centre for Science Education and Research (NUCSER), Paneer Campus, Deralakatte, Mangaluru, Karnataka 575018, India 2 Department of Biochemistry, College of Medicine and Health Sciences, National University of Science and Technology, Sahar, Oman 3 Research Unit, Mangalore Institute of Oncology, Mangalore, Pinto Lane, Karangalpady, Karnataka-575002, India 4 Department of Pharmacology, Amrita Institute of Medical Sciences, Vishwa Vidyapeetham, Kerala-682041, India 5 Department of Pharmacology, Indira Gandhi Institute of Medical Sciences (IGIMS), Sheikhpura, Patna, Bihar-800014, India 6 Department of Pharmacology, Amrita Institute of Medical Sciences, Vishwa Vidyapeetham, Kerala-682041, India 7 Research Unit, Mangalore Institute of Oncology, Mangalore, Pinto Lane, Karangalpady, Karnataka-575002, India
- Source: Metabolites of Medicinal Plants: Insightful Approaches , pp 211-231
- Publication Date: December 2024
- Language: English


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Infection with Helicobacter pylori poses a threat to public health in numerous regions of the world. This bacterium has been linked to a wide range of stomach disorders, some of which are benign, such as superficial gastritis, while others are rather serious, including chronic atrophic gastritis, stomach cancer, and peptic (gastric or duodenal) ulcers. These conditions can vary in severity and cause significant morbidity in the affected individual. The International Agency for Research on Cancer designated it as a 'Group I carcinogen' in the year 1994 after concluding that it played a significant role in the development of stomach cancer. As a result, there has been a considerable focus on discovering ways to prevent H. pylori infections. In this article, we discuss the role that H. pylori plays in human gastric disease, with a particular focus on the impact of dietary agents on preventing infection and on the pathogenesis of H. pylori.
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