Targeting Inflammatory Biomarkers and Free Radicals by Anthocyanins
- Authors: Hitesh Malhotra1, Rudrakash2, Tanu Devi3
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View Affiliations Hide Affiliations1 Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, India 2 Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, India 3 Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, India
- Source: Anthocyanins: Pharmacology and Nutraceutical Importance , pp 68-83
- Publication Date: November 2024
- Language: English
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Inflammation and oxidative stress are synergistic partners in the etiopathogenesis of diverse diseases. Polyphenols, such as anthocyanins, are responsible for the regulation of the inflammatory process and activation of the endogenous antioxidant defense system. Anthocyanins modulate the level of inflammatory markers and exert an anti-inflammatory effect. Consequently, translating the research outcomes into clinical practice significantly contributes to the prevention and management of chronic diseases. The chapter summarizes the role of anthocyanins as anti-inflammatory and anti-oxidative molecules in both health and diseases. Anthocyanins downregulate pro-inflammatory markers in chronic disease and thus suppress inflammation as well as oxidative stress in inflammatory disorders. The chapter can help researchers and other healthcare professionals to understand the importance of anthocyanin use in chronic diseases.
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