Multi-omics Profiles are Applicable to Human Diseases and Drug Development
- Authors: Adriana Montserrat Espinosa González1, Jos del Carmen Benítez-Flores2, Juan Carlos Gómez-Verjan3, Nadia Alejandra Rivero-Segura4, Ignacio Peñalosa Castro5, Jose Cruz Rivera Cabrera6, Edgar Antonio Estrella-Parra7
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View Affiliations Hide Affiliations1 Phytochemistry Laboratory, UBIPRO, Superior Studies Faculty (FES)-Iztacala, National Autonomous University of Mexico (UNAM), Tlalnepantla de Baz, Mxico State, 54090, Mxico 2 Histology Laboratory 1, UMF, Superior Studies Faculty (FES)-Iztacala, National Autonomous University of Mexico (UNAM), Tlalnepantla de Baz, Mexico City, Mexico State, 54090, Mxico 3 National Institute of Geriatrics (INGER), Blvd. Adolfo Ruiz Cortines 2767, Mxico City, 10200, Mxico 4 National Institute of Geriatrics (INGER), Blvd. Adolfo Ruiz Cortines 2767, Mxico City, 10200, Mxico 5 Phytochemistry Laboratory, UBIPRO, Superior Studies Faculty (FES)-Iztacala, National Autonomous University of Mexico (UNAM), Tlalnepantla de Baz, Mxico State, 54090, Mxico 6 Liquid Chromatography Laboratory, Department of Pharmacology, Military School of Medicine, CDA, Palomas S/N, Lomas de San Isidro, 11200, Mxico City, Mxico 7 Phytochemistry Laboratory, UBIPRO, Superior Studies Faculty (FES)-Iztacala, National Autonomous University of Mexico (UNAM), Tlalnepantla de Baz, Mxico State, 54090, Mxico
- Source: Biotechnology and Drug Development for Targeting Human Diseases , pp 1-19
- Publication Date: March 2024
- Language: English
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Traditional medicine has been a reliable source for the discovery of molecules with therapeutic activity against human diseases of clinical interest. In the past, knowledge of traditional medicine was mainly transmitted orally and in writing. Recently, the advent of "multiomics" tools (transcriptomics, metabolomics, epigenomics, proteomics, and lipidomics, among others) has increased and merged our knowledge, both traditional knowledge and that gained with these new multiomics technologies. In this way, the development of medicines with these 'multiomics technologies' has allowed pharmaceutical advances in the discovery of new drugs. In addition, 'multiomics' technologies have made it possible to uncover new biological activities of drugs that are currently used in clinical therapy. In the same way, 'multiomics' has allowed for the development of 'personalized medicine', that is, a particular and specific treatment and/or diagnosis of a patient with respect to a disease. Therefore, 'multiomics' technologies have facilitated the discovery of new clinical therapeutics for disease, as well as allowing for the diagnosis and/or treatment of diseases in an individual and personalized way. <br>
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