Immunomodulatory Potential of Himalayan Plant: Withania somnifera
- Authors: Kavita1, Naina Rajak2, Praveen Kumar3, Shikha Singh4, Neha Garg5
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View Affiliations Hide Affiliations1 Department of Medicinal Chemistry, Faculty of Ayurveda, Institute of Medical Sciences, BanarasHindu University, Varanasi, Uttar Pradesh 221005, India 2 Department of Medicinal Chemistry, Faculty of Ayurveda, Institute of Medical Sciences, BanarasHindu University, Varanasi, Uttar Pradesh - 221005, India 3 Department of Medicinal Chemistry, Faculty of Ayurveda, Institute of Medical Sciences, BanarasHindu University, Varanasi, Uttar Pradesh - 221005, India 4 Department of Prasuti Tantra, Faculty of Ayurveda, Institute of Medical Sciences, BanarasHindu University, Varanasi, Uttar Pradesh-221005, India 5 Department of Medicinal Chemistry, Faculty of Ayurveda, Institute of Medical Sciences, BanarasHindu University, Varanasi, Uttar Pradesh - 221005, India
- Source: Bioactive Phytochemicals from Himalayas: A Phytotherapeutic Approach , pp 105-116
- Publication Date: January 2023
- Language: English
Immunomodulatory Potential of Himalayan Plant: Withania somnifera, Page 1 of 1
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Withania somnifera, a herb used in Ayurveda since ancient times, is commonly found in the Himalayan belt. Withania somnifera is reported to be useful in fever, arthritis, asthma, bronchitis, tuberculosis, syphilis, and cancers. Its leaves are found to be effective against swelling, chest pain, sores, and ulcers. Withania possesses antioxidant, immunomodulatory, anti-inflammatory, anti-stress, anti-bacterial, antimicrobial, anti-fungal, anti-tumor, adaptogenic, and memory-enhancing properties. Among the bioactive compounds present in Withania, Withaferin A is the most important and well-explored compound having anti-cancer activity among several other activities. Many studies have reported the anti-inflammatory action of Withania somnifera and isolated Withaferin A. In this chapter, we have summarized the antiinflammatory activities exhibited by this multifaceted medicinal plant.
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