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Multi-omics Data Integration: Applications in Systems Genomics

- Authors: Anam Naz1, Ammara Siddique2, Aqsa Ikram3, Bisma Rauff4, Huma Tariq5, Sajjad Ahmed6
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View Affiliations Hide Affiliations1 Institute of Molecular Biology and Biotechnology (IMBB), The University of Lahore (UOL), Lahore, Pakistan 2 Atta ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), Islamabad, Pakistan 3 Institute of Molecular Biology and Biotechnology (IMBB), The University of Lahore (UOL), Lahore, Pakistan 4 Department of Biomedical Engineering, University of Engineering and Technology (UET), Lahore, Narowal Campus, Pakistan 5 Department of Zoology, Hazara University, Manshera, Pakistan 6 Department of Health and Biological Sciences, Abasyn University, Peshawar, Pakistan
- Source: Omics Technologies for Clinical Diagnosis and Gene Therapy: Medical Applications in Human Genetics , pp 137-155
- Publication Date: October 2022
- Language: English
Interpretation of molecular differences and intricacy at multiple stages, for instance proteome, genome, epigenome, metabolome, and transcriptome is needed for a thorough understanding of disease and human health. Biology has been reliant on data produced at these stages, which is collectively referred to as multi-omics data, after the emergence of sequencing techniques. Among all the aspects of biology, rapid development in high-throughput data initiation has enabled to carry out research on multi-omics systems biology. Metabolomics, proteomics, and transcriptomics data can provide answers to the targeted biological queries about the expression of metabolites, proteins, and transcripts, independently. A concise summary of multi-omics data sources, challenges in datasets integration, and visualization portals is also discussed.
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