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Pharmacogenomics
- Authors: Shumaila Azam1, Sahar Fazal2, Attiya Kanwal3, Muhammad Saad Khan4, Narjis Khatoon5, Muneeba Ishtiaq6, Rabbiah Manzoor Malik7, Sana Elahi8, Fakhra Nazir9
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View Affiliations Hide AffiliationsAffiliations: 1 Department of Bioinformatics and Biosciences, Capital University of Science and Technology, (CUST), Islamabad, Pakistan 2 Department of Bioinformatics and Biosciences, Capital University of Science and Technology, (CUST), Islamabad, Pakistan 3 International Islamic University Islamabad (IIUI), Islamabad, Pakistan 4 Department of Biosciences, COMSATS University Islamabad, Sahiwal, Pakistan 5 Department of Bioinformatics and Biosciences, Capital University of Science and Technology, (CUST), Islamabad, Pakistan 6 Department of Bioinformatics and Biosciences, Capital University of Science and Technology, (CUST), Islamabad, Pakistan 7 Department of Bioinformatics and Biosciences, Capital University of Science and Technology, (CUST), Islamabad, Pakistan | Wah Medical College, WahCantt, Pakistan 8 Department of Bioinformatics and Biosciences, Capital University of Science and Technology, (CUST), Islamabad, Pakistan 9 Department of Bioinformatics and Biosciences, Capital University of Science and Technology, (CUST), Islamabad, Pakistan | Centre for Bioresource Research, Islamabad, Pakistan
- Source: Omics Technologies for Clinical Diagnosis and Gene Therapy: Medical Applications in Human Genetics , pp 174-189
- Publication Date: October 2022
- Language: English
The ongoing development in new genotyping methods necessitates an understanding of their potential benefits and limits in terms of pharmacogenomics utility. We give an overview of technologies that can be used in pharmacogenomics research and clinical practice in this chapter. The Human Genome Projects completion has paved the way for the development of clinical instruments for patient evaluation. Pharmacogenomics may enable the identification of patients who are most likely to benefit from a specific drug, as well as those for whom the expense and risk are greater than the advantages. Both drug therapys safety and efficacy may improve. In the future, genotyping may be used to tailor drug treatment for large groups of individuals, lowering drug treatment costs and improving therapeutic efficacy and overall health.
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