Naturally-occurring Bioactive Molecules with Anti- Parkinson Disease Potential
- Authors: Atul Kabra1, Kamal Uddin2, Rohit Sharma3, Ruchika Kabra4, Raffaele Capasso5, Caridad Ivette Fernandez Verdecia6, Christophe Hano7, Natália Cruz-Martins8, Uttam Singh Baghel9
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View Affiliations Hide AffiliationsAffiliations: 1 School of Pharmacy, Raffles University, Neemrana, Alwar 301020 (Rajasthan), India 2 Aligarh College of Pharmacy, Aligarh-202002 (U.P), India 3 Department of Rasa Shastra and Bhaishjya Kalpana, Faculty of Ayurveda, IMS, Banaras Hindu University, Varanasi, 221005 (U.P), India 4 School of Pharmacy, Raffles University, Neemrana, Alwar-301020 (Rajasthan), India 5 Universita Degli Studi di Napoli Federico II, Naples, Italy 6 International Center of Neurological Restoration (CIREN), Basic Division, La Habana, Cuba 7 Laboratoire de Biologie des Ligneux et des Grandes Cultures, INRAUSC 1328, Université d’ Orléans, 45100 Orléans, France 8 Faculty of Medicine, University of Porto, Porto, Portugal 9 Department of Pharmacy, University of Kota, Kota-324005 (Rajasthan), India
- Source: Indopathy for Neuroprotection: Recent Advances , pp 5-38
- Publication Date: December 2022
- Language: English
Parkinson's disease (PD) is a complex limiting neurodegenerative disorder, with a rising incidence. Current therapeutic options for PD have multiple limitations, and naturally occurring biomolecules, often known as phytochemicals, with potent neuroprotective activities, have been searched to meet the need. Thus, this chapter encompasses in-depth information on reported anti-PD activities of medicinal plants in light of available pre-clinical and clinical studies and shares the mechanisms of action proposed in fighting PD. Published information from PubMed, Scopus, Science Direct, Springer, Google Scholar, and other allied databases was analyzed. There is rising interest among researchers in investigating medicinal plants and their isolated compounds for their anti-PD efficacy. Scattered information about the anti-PD potential of plants and bioactive compounds is reported in the scientific domain. A total of 92 medicinal plants belonging to 63 families, exhibiting anti-PD activity were discussed. Botanical species have revealed an extreme potential, encouraging future examination. Data discussed here can be used for further research and clinical purposes.
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