Introduction of Diagnostic Approach for Systemic Lupus Erythematosus

Musculoskeletal symptoms occur in up to 90% of systemic lupus erythematosus (SLE) patients. Lesions extend not only to joints but to the whole body, causing inflammation in diverse organs such as the skin, kidneys, lungs, nervous system, serous membranes and virtually across all organs of the body. The ABCDEFGHI method consists of A (Alignment): malalignment and deformation; B (Bone): bone changes; C (Capsular lesions): cartilage and intra-articular lesions; D (Distribution): four dimensional distributions: 1 intra-articular, 2 Intra region, 3 intrabody, 4 timeline; E (Extra-bone): extra-articular soft tissue; F (Further information): further additional medical information; G (Goal): general analysis and integrated, a comprehensive diagnosis from the information; H (Heal and Heath): treatment and prognosis; and I (Immunological analyzes): immunological interpretation (cytokines and phenotypes of immune cells). This chapter outlines a methodology for diagnosing the musculoskeletal and systemic manifestations of SLE.