Multicomponent Synthesis of Heterocycles by Microwave Irradiation
- Authors: Alice Rinky Robert1, Ganja Himavathi2, Maddila Suresh3
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View Affiliations Hide Affiliations1 Department of Chemistry, GITAM Institute of Sciences, GITAM (deemed to be University), Visakhapatnam, Andhra Pradesh, India 2 School of Chemistry & Physics, University of KwaZulu Natal, Westville Campus, Chiltern Hills, Durban 4000, South Africa 3 Department of Chemistry, GITAM Institute of Sciences, GITAM (deemed to be University), Visakhapatnam, Andhra Pradesh, India
- Source: Advances in Organic Synthesis: Volume 17 , pp 1-52
- Publication Date: July 2022
- Language: English
Multicomponent Synthesis of Heterocycles by Microwave Irradiation, Page 1 of 1
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The multicomponent reactions (MCRs) are vital for producing structurally varied molecular objects. Multicomponent reactions (MCRs) contain three or more synthetic stages and are carried out without isolation of any intermediate, thus requiring mild reaction conditions. They are eco-friendly and cost-effective, have a short reaction time, produce higher yields, and require raw materials. The use of microwave irradiation in green organic synthesis sustains some of the aims of "green and sustainable chemistry." It offers several benefits over the conventional approach in reducing time, reaction rates, selectivity, product yields, etc. Consequently, the preparation of various heterocycles using a one-pot multicomponent method combined with the application of microwave irradiation is one of the best areas amongst synthetic chemistry. The present study illustrates an overview of recent progress on microwave irradiated, one-pot multicomponent synthesis of heterocycles.
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