Behavioral and Non-behavioral Models of Depression: Current Scenario And Future Directions

- Authors: Sudha1, Dinesh Dhingra2, Anil Kumar3, Monu Yadav4
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View Affiliations Hide Affiliations1 Department of Pharmaceutical Science, Guru Jambheshwar University of Science and Technology, Hisar 125001, India 2 Department of Pharmaceutical Science, Guru Jambheshwar University of Science and Technology, Hisar 125001, India 3 Pharmacology Department, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Studies (UGC CAS), Panjab University, Chandigarh 160014, India 4 Pharmacology Department, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Studies (UGC-CAS), Panjab University, Chandigarh 160014, India
- Source: Animal Models for Neurological Disorders , pp 52-64
- Publication Date: December 2021
- Language: English


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Animal models help understand the possible pathways involved in a disease's pathophysiology, and they offer a significant test to screen the potential of a therapeutic compound. Depression is a chronic mental illness that affects the world's population widely. There are different behavioral and non-behavioral models of depression used in experimental animals to explore and understand the primary mechanism of depression. These models produce different types of depressive symptoms that can correlate with human depressive symptoms. This study highlights the stress and non-stress models by distinguishing the merits and demerits of models used for depression.
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