West Nile Virus
- Authors: Abdullah Iqbal1, Shumaila Manzoor2, Muhammad Abubakar3
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View Affiliations Hide Affiliations1 Livestock and Dairy Development Department, Lahore, Punjab, Pakistan 2 National Veterinary Laboratory, Islamabad, Pakistan 3 National Veterinary Laboratory, Islamabad, Pakistan
- Source: Emerging Trends in Veterinary Virology , pp 81-89
- Publication Date: March 2022
- Language: English
West Nile Virus, Page 1 of 1
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West Nile virus (WNV) is an arthropod-borne RNA virus, first time isolatedin 1937 from Uganda. Now, WNV has been reported from throughout the world viruswith 9 possible phylogenetic lineages. Mosquitoes of the genus Culex are mainlyresponsible for WNV transmission to birds and humans. In horses, WNV cause thedisease, and the infected horse suffers from lethargy and nervous disorder. WNVcauses West Nile virus disease in humans, which is characterized by skin rash, fever,vomiting and sometimes neurological disorder. In contrast to the WNV vaccine inanimals, no vaccine against WNV is commercially available for humans. For veterinaryuse, RecombiTEK is a commercially available recombinant vaccine against WNV.WNV can be detected in horses by serological tests like hemagglutination inhibition,ELISA, and plaque reduction neutralization or by necropsy of the brain. People whohave direct contact with birds and horses are more prone to WNV exposure than others.
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