Metabolomics and Precision Medicine
- Authors: James Reigle1, Khyati Mehta2, Somchai Chutipongtanate3
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View Affiliations Hide Affiliations1 Department of Biomedical Informatics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, United States 2 Division of Pathology and Laboratory Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States 3 Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, United States
- Source: Recent Advances in Molecular and Translational Medicine: Updates in Precision Medicine , pp 118-133
- Publication Date: December 2021
- Language: English
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Metabolomics is a growing "omics" field in investigational research and clinical care. Metabolomics is the study of metabolome, including both endogenous and exogenous small molecules generated in the body viametabolic processes. This discipline is young compared to its complements, such as genomics or transcriptomics. However, it promises to be a powerful tool for understanding normal and diseased physiological states and informing clinicians in diagnosing and treating patients. This chapter summarizes the concept of metabolomics, describes the metabolomic approaches, and provides a practical workflow of metabolomic data analysis to illustrate the current and potential applications of metabolomics in precision medicine.
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