Stem Cell Engineering Ability to Promote Cardiac Regenerative Activity
- Authors: Ranjita Misra1, Fahima Dilnawaz2
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View Affiliations Hide Affiliations1 Centre for Molecular and Nanomedical Sciences, Sathyabama Institute of Science and Technology, Chennai 600119, Tamil Nadu, India 2 Laboratory of Nanomedicine, Institute of Life Sciences, Nalco Square, Chandrasekharpur, Bhubaneswar-751023, Odisha, India
- Source: Nanomedicinal Approaches Towards Cardiovascular Disease , pp 144-159
- Publication Date: July 2021
- Language: English
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The heart of adult humans is usually less capable of regeneration; several strategies have been used for the repairment of a damaged heart and to recover its function. However, stem cell technology showed a promising approach for cardiac therapy. More advanced strategies are used for improved stem cell-mediated cardiac regenerative therapy and to develop vascularization between scaffold (established by 3D engineered techniques) and host hearts. Through understanding the cellular and molecular mechanisms regulating heart regeneration, considerable progress has been made, which offers potentiality in controlling cardiac remodeling and redirecting the adult human heart towards a regenerative state.
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