Tetracyclic Benzocarbazoles and Derivatives: Synthesis and Applications
- Authors: Francisco Vilaça Gaspar1, Joseane Alves Mendes2, Paulo Roberto Ribeiro Costa3, Miguel Yus4, Francisco Foubelo5, Camilla Djenne Buarque6
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View Affiliations Hide Affiliations1 Laboratory of Bioorganic Chemistry, Nucleus of Research of Natural Products, Health Science Center, Federal University of Rio de Janeiro UFRJ, CEP 21941 590, Rio de Janeiro, Brazil 2 Departamento de Qumica Orgnica, Instituto de Sntesis Orgnica, and Centro de Innovacion en Qumica Avanzada (ORFEO CINQA), Universidad de Alicante, Apdo. 99, 03080 Alicante, Brazil 3 Laboratory of Bioorganic Chemistry, Nucleus of Research of Natural Products, Health Science Center, Federal University of Rio de Janeiro UFRJ, CEP 21941-590, Rio de Janeiro, Brazil 4 Departamento de Qumica Orgnica, Instituto de Sntesis Orgnica, and Centro de Innovacion en Qumica Avanzada (ORFEO CINQA), Universidad de Alicante, Apdo. 99, 03080 Alicante, Brazil 5 Laboratory of Bioorganic Chemistry, Nucleus of Research of Natural Products, Health Science Center, Federal University of Rio de Janeiro UFRJ, CEP 21941-590, Rio de Janeiro, Brazil 6 Department of Chemistry, Pontifical Catholic University of Rio de Janeiro Puc-Rio, CEP 22435- 900 Rio de Janeiro, Brazil
- Source: Frontiers in Natural Product Chemistry: Volume 7 , pp 158-196
- Publication Date: November 2021
- Language: English
Tetracyclic Benzocarbazoles and Derivatives: Synthesis and Applications, Page 1 of 1
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Tetracyclic benzocarbazoles are examples of nitrogen-containing heterocycles, which display interesting pharmacological activities and physicochemical properties. This chapter aims to bring some examples about the synthesis of bezocarbazoles, mostly benzo[a]carbazoles (including the dihydro and tetrahydro derivatives), with interesting properties. This chapter also includes aza-pterocarpans and aza-coumestans, which are structurally similar to benzo [a] carbazoles, although their analogous natural products are formed through different biosynthetic pathways. Being aware of the potential interest of these compounds, many efforts have been made for the development of new methodologies to carry out their synthesis and will be discussed below.
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