Recent Advances in the Synthesis of N-Glycosyl Compounds
- Authors: Nuno M. Xavier1, Rafael Nunes2
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View Affiliations Hide Affiliations1 Centro de Qumica e Bioqumica, Faculdade de Cincias, Universidade de Lisboa, Ed. C8, 5 Piso, Campo Grande, 1749 016 Lisboa, Portugal. 2 Centro de Qumica e Bioqumica, Faculdade de Cincias, Universidade de Lisboa, Ed. C8, 5 Piso, Campo Grande, 1749 016 Lisboa, Portugal.
- Source: Advances in Organic Synthesis: Volume 10 , pp 99-138
- Publication Date: September 2018
- Language: English
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N-Glycosyl compounds, analogs of glycosides possessing an N-glycosidic linkage, have attracted much attention as synthetic targets in medicinal chemistry, due to their biological activities. In this chapter, the synthesis of non-nucleosidic Nglycosyl compounds is reviewed. The groups of molecules covered herein include Nglycosylamines/ amides, sulfonamides, hydrazines, phosphoramidates and Nglycosylamino acids, among other related derivatives. Methods for their access, based on the literature from the last 20 years, as well as their relevance as bioactive substances, are focused.
Hardbound ISBN:
9781681087443
Ebook ISBN:
9781681087436
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