Stem Cells in Endocrinology: Facts and Future

- Authors: Hugo Mendieta Zeron1, Araceli Hinojosa Juarez, Joel Vargas Hernandez
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View Affiliations Hide Affiliations1 Faculty of Medicine, Autonomous University of the State of Mexico (UAEMex), "Mónica Pretelini Sáenz" Maternal Perinatal Hospital (HMPMPS) and Cipres Grupo Medico S.C. (CGM), Toluca, Mexico.
- Source: Frontiers in Stem Cell and Regenerative Medicine Research: Volume 8 , pp 150-167
- Publication Date: August 2018
- Language: English


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The main characteristic of a stem cell is its multipotency that has to be demonstrated experimentally as follows: I) the differentiation pathway can be characterized by specific surface receptor expression; II) it is possible to generate lineage-specific cells in vitro, and III) in a depleted organ the repopulation process can be reached in vivo. In this regard, the scientific activity to propose and improve techniques of stem cell transplant focused on its clinical application in the endocrinological field is being studied extensively. Unfortunately, not a lot is known about stem cell transplantation to cure diseases and we depend a lot on murine studies. The aim of this chapter is to review some of the most important research lines about stem cells that could have a clinical application in endocrinology.
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