The Biological Activities and Synthesis of 2,6- Disubstituted Piperidinols

- Authors: Yasunao Hattori, Hidefumi Makabe2
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View Affiliations Hide Affiliations2 Sciences of Functional Foods, Graduate School of Agriculture, Shinshu University, 8304 Minamiminowa, Kami ina, Nagano 399-4598, Japan
- Source: Frontiers in Natural Product Chemistry: Volume 3 , pp 196-220
- Publication Date: August 2017
- Language: English


The Biological Activities and Synthesis of 2,6- Disubstituted Piperidinols, Page 1 of 1
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2,6-Disubstituted piperidinols are one of the most investigated groups of compounds owing to their potential therapeutic use and unique structures. They show a wide variety of biological activities, including inhibition of superoxide anion production, influence on the central nervous system, antibacterial, and plant growth inhibition. For these reasons, 2,6-disubstituted piperidinols have attracted attention from medicinal, phyto-, and synthetic organic chemists. In this review, the biological profile and chemistry of 2,6-disubstituted piperidinols are described. Recent developments in synthetic methods for 2,6-disubstituted piperidinols are also discussed.
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