Pharmacotherapy for Inflammatory Processes
- Authors: Graham A. Mackay1, Alastair G. Stewart2
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View Affiliations Hide Affiliations1 Department of Pharmacology & Therapeutics and Lung Health Research Centre, University of Melbourne, Parkville, Victoria 3010, Australia 2 Department of Pharmacology & Therapeutics and Lung Health Research Centre, University of Melbourne, Parkville, Victoria 3010, Australia
- Source: Basic Biology and Clinical Aspects of Inflammation , pp 377-426
- Publication Date: March 2016
- Language: English
Pharmacotherapy for Inflammatory Processes, Page 1 of 1
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Drugs that dampen acute and chronic inflammation and their sequelae are currently some of the most widely utilised therapeutic agents. With the increasing appreciation that inflammation is involved in the pathobiology of most of the serious and complex disorders that affect mankind, the development and therapeutic uses of anti-inflammatory drugs will likely grow with increasing demand for precision interventions in inflammatory pathways. In this article, we examine commonly utilised anti-inflammatory drugs with a view to how their efficacy has informed our fundamental understanding of inflammatory mediators and pathways. We then look at more recently developed, or developing, targeted strategies that have emerged from a deeper appreciation of these pathways.
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