Contribution of Stem Cells to Dental Tissue Regeneration: Isolation, Function, and Application

- Authors: Atsushi Tomokiyo1, Naohisa Wada2, Hidefumi Maeda3
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View Affiliations Hide Affiliations1 Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Higashi ku, Japan. 2 Division of General Oral Clinic, Kyushu University Hospital, Higashi-ku, Japan 3 Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Higashi ku, Japan.
- Source: Frontiers in Stem Cell and Regenerative Medicine Research: Volume 2 , pp 3-38
- Publication Date: April 2016
- Language: English


Contribution of Stem Cells to Dental Tissue Regeneration: Isolation, Function, and Application, Page 1 of 1
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Tooth loss due to periodontitis, traumatic injury, or deep caries can cause facial aesthetic problems and difficulties with mastication. The ultimate goal of dental prosthetic treatment is to generate fully functioning organs to replace dental tissue that has been lost or damaged due to disease, injury or aging. Tissue engineering is a rapidly expanding field of applied biology and biomedical sciences, which aims to replace defective tissues with newly-generated tissue by combining cells, scaffolds, and biologically active molecules. Stem cells hold great promise for tissue engineering owing to their multipotency and self-renewal ability. In this article, we will present the current progress in stem cell-based dental tissue regeneration and elaborate on the potential of dental stem cells for clinical application.
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