Advances in the Synthesis of Organometallic Amino Acids and Analogues
- Authors: Poulami Jana1, Sibaprasad Maity2, Debasish Haldar3
-
View Affiliations Hide Affiliations1 Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, West Bengal 741252, India 2 Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, West Bengal 741252, India 3 Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, West Bengal 741252, India
- Source: Advances in Organic Synthesis: Volume 5 , pp 355-378
- Publication Date: January 2013
- Language: English
Advances in the Synthesis of Organometallic Amino Acids and Analogues, Page 1 of 1
< Previous page | Next page > /docserver/preview/fulltext/9781608054800/chapter-8-1.gif
Incorporation of metal chelating amino acids in protein or peptide sequences helps protein purification due to the metal ion affinity of the protein or peptide. Structure and function of synthetic amino acids with side chain metal complexes have particular importance for extending our understanding of organometallic compounds under physiological conditions and mimic protein folding and stabilization. Chemists are now designing biomimetic organo-metallic amino acids that can form both secondary and tertiary structures through various noncovalent interactions. An overview of the design and synthesis of non-proteinogenic amino acids containing metal ions in the side chain is discussed.
-
From This Site
/content/books/9781608054800.chapter-8dcterms_subject,pub_keyword-contentType:Journal -contentType:Figure -contentType:Table -contentType:SupplementaryData105
