An Update on Trifluoromethylation of Carbonyl Compounds
- Authors: Nubia Boechat1, Monica Macedo Bastos2
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View Affiliations Hide Affiliations1 Fundao Oswaldo Cruz, Farmanguinhos, Rua Sizenando Nabuco, 100 CEP 21041 250 Manguinhos - Rio de Janeiro, RJ, Brazil 2 Fundao Oswaldo Cruz, Farmanguinhos, Rua Sizenando Nabuco, 100 CEP 21041 250 Manguinhos - Rio de Janeiro, RJ, Brazil
- Source: Advances in Organic Synthesis: Volume 5 , pp 279-308
- Publication Date: January 2013
- Language: English
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This chapter reviews the recent findings on the synthetic methods developed for the direct introduction of a trifluoromethyl group in carbonyl compounds. It was organized by type of reagent highly considering the description of the trifluoromethylating agents, their activation mode, their asymmetric approaches, as well as applications in organic synthesis.
Hardbound ISBN:
9781608056187
Ebook ISBN:
9781608054800
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