oa Metabonomic Analysis in Liver Diseases
- Authors: Laia Chavarria1, Ignasi Barba2, Juan Córdoba3
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View Affiliations Hide Affiliations1 Liver Unit, Hospital Vall Hebron, Barcelona, Spain 2 Liver Unit, Hospital Vall Hebron, Barcelona, Spain 3 Liver Unit, Hospital Vall Hebron, Barcelona, Spain
- Source: Functional Molecular Imaging In Hepatology , pp 76-86
- Publication Date: May 2012
- Language: English
Metabonomic Analysis in Liver Diseases, Page 1 of 1
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Metabonomics is a new technology that provides rapid, accurate and precise analysis of a large number of metabolites in biological systems. Using multivariate analysis and pattern recognition, it provides a direct unbiased measure of biochemical consequences of pathology or drug treatment. The integration of the all omics information (genomics, transcriptomics, proteomics and metabonomics) can provide knowledge for better understanding of biological systems and may lead to the generation of new mechanistic hypotheses to explain the development of pathologies. In this chapter, we will give an overview of the basic principles of this new technology and provide examples of applications in liver diseases.
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