Chemical Synthesis of Oligo-(1→3)-β-D-Glucans
- Authors: Vincent Ferrières1, Laurent Legentil, Balla Sylla, Karine Descroix, Caroline Nugier Chauvin, Richard Daniellou
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View Affiliations Hide Affiliations1 Ecole Nationale Suprieure de Chimie de Rennes, CNRS, UMR 6226, Universiteuropenne de Bretagne, France
- Source: Beta-Glucan, Structure, Chemistry and Specific Application , pp 83-101
- Publication Date: May 2013
- Language: English
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The synthesis of β-(1→3)-glucans is at present has more than a chemical challenge. The discovery of their biological properties found development for new anticancer therapies, the efficient preparation of pure and structurally well-defined β-(1→3)-glucans has generated interest in the glycochemist community. This chapter highlights recent strategies that not only yielded the target biomolecules but have also drawn attention on basic limitations. It also shows how it is possible to strengthen the activity of β-glucans by conjugation to non saccharidic derivatives.
Hardbound ISBN:
9781608053018
Ebook ISBN:
9781608052608
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