Biocatalysis in Organic Synthesis
- By Robert Azerad1
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View Affiliations Hide Affiliations1 Groupe de Biocatalyse, Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, UMR CNRS 8601, Universite Rene Descartes Paris V, 45 rue des Saints Peres, 75006 Paris, , France
- Source: Advances in Organic Synthesis: Volume 1 , pp 455-518
- Publication Date: December 2004
- Language: English
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Biocatalytic reactions using enzymes or whole microbial cells are increasingly employed for organic synthesis, taking advantage of their high versatility and exquisite selectivities (chemo-, regio- and stereoselectivity). Resolution of racemates and its refinements, desymmetrisation of meso- and prochiral compounds by oxidoreduction, some C-C bond forming reactions and other miscellaneous reactions will be outlined, illustrating the most characteristic aspects of environmentally friendly and yield-effective production of commodity chemicals, stereospecific building blocks or intermediates, and competitive step-replacement strategies for asymmetric syntheses.
Hardbound ISBN:
9781608056439
Ebook ISBN:
9781608051977
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