Therapeutic Approach of Histamine H3 Receptors in Obesity
- Authors: Takayuki Masaki, Hironobu Yoshimatsu2
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View Affiliations Hide Affiliations2 Department of Internal Medicine 1, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Yufu-Hasama, Oita, 879-5593, Japan
- Source: Frontiers in CNS Drug Discovery: Volume 1 , pp 537-542
- Publication Date: August 2010
- Language: English
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Obesity is considered as one of the risk factors for metabolic disorders. There is an increasing evidence that obesity is under control of several cytokines and hormone in the brain. Brain histamine and H3 receptors are important factors for regulating obesity. The results of physiological and pharmacological studies revealed that brain histamine and H3 receptors are involved in the regulation of obesity. In this review, we describe the implication and patent for developing H3 receptor antagonists and their therapeutic potential of obesity.
Hardbound ISBN:
9781608053636
Ebook ISBN:
9781608051595
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