Bentham Science Publishers

The natural world can be viewed as a continuously changing complex system comprising variable units that do not conform to any stable plan. Within this framework, human evolution is not the story of the past that created Homo sapiens and then handed this account over to written history. It is the ongoing process that shapes us now and will shape us in the future, body and mind. We must understand it in order to survive and be able to direct it to our advantage. The Dynamic Human presents a general theory of how humans function as a multi-individual system embedded in the natural world. The authors employ a unified approach of systems theory to outline forces that direct ongoing human evolution and produce its outcomes in terms of the past, present and future. Readers will find a perspective on the human place in nature, through a brief account of the past human evolution over 10 million years ago, a discussion of the earliest appearance of humans some 2 million years ago, and a description of the mechanisms of the changes in the gene pool of humans from generation-to-generation. Understanding the forces involved in these mechanisms (physical and mental growth and development) may allow us to understand world better. The Dynamic Human presents a simplified perspective on human evolution for all readers interested in a discourse on the origins, nature and future of human beings.

This Ebook focuses theoretically, empirically and practically on a concept of the self that includes neurobiological, psychological and social dimensions in psychotherapy with adults. The theoretical perspective on the self that is developed in the Ebook can be the basis for how a therapist may use himself/herself professionally in a therapeutic relationship. It is expected that the book will be of interest to many persons in this field.

The Evolution of Radionanotargeting towards Clinical Precision Oncology is a remarkable book honoring Professor Kalevi Kairemo, who is known among academic and medical circles as a pioneer in novel radiolabeled therapeutics. This festschrift provides an overview of key advances in the field of radionanotargeting, and the directions for future development in patient care. Prof Kairemo's research is based on multiomics, which involves multiple elements: genomics, transcriptomics, proteomics, metabolomics, microbiomics, epigenomics, exposome, imaging, and precision medicine, which is reflected by the unique collection of articles presented. The articles start from the angle of radionanotargeting and theragnostics leading to imaging and therapy, which includes sections for thyroid cancer, head and neck cancer, genitourinary cancers and neuroendocrine neoplasms. Theragnostics, nanoparticles and precision oncology have also been covered in their own segments, while also giving a glimpse of research in metabolic imaging, cardiovascular radionuclide imaging, and bone therapies. The sequence of chapters demonstrates how, through Professor Kairemo's efforts, radionanotargeting has evolved to a practice changing therapeutic approach in the clinic, particularly in oncology. Finally, Professor Kairemo's own memoir, Seven decades in health care and memoirs from colleagues including a personal introduction to him with a photographic cavalcade reveals the world of a multitasking person with a multidisciplinary approach to science, that ushered his development of significant expertise across the fields of chemistry, biology, engineering, physics and clinical medicine. This book is excellent for medical historians, trainees and specialists in clinical and radiological oncology in expanding their understanding of the role of radionuclide imaging over the years, making it an ideal tribute that belongs in the library of anyone involved in the field.

The Fertility Promise is a complete guide to the often emotional, expensive and confusing process of fertility treatment. The book offers clear explanations and advice to anyone undergoing fertility treatment (such as in vitro fertilization) or anyone seeking information about relevant treatment options. The information includes advice to both male and female patients, LGBT patients, IVF clinics, the IVF treatment process, the issues surrounding IVF ‘add-ons’, what it is really like to go through fertility treatment and what the future of IVF might look like. Covering every aspect of the topic, the book is an extremely important point of reference for all fertility patients as well as individuals who wish to broaden their perspective on fertility medicine and clinics. The Fertility Promise informs both general readers and empowers fertility patients who are looking for the correct treatment, enabling them to clearly understand the fertility treatment process and to ask appropriate and often revealing questions on the subject.

The Future of Agriculture: IoT, AI and Blockchain Technology for Sustainable Farming explores how cutting-edge technologies like Artificial Intelligence (AI), the Internet of Things (IoT), and Blockchain are transforming farming for a sustainable future. Addressing challenges such as climate change, resource scarcity, and food supply chain inefficiencies, the book highlights how these technologies can improve decision-making, enhance crop yields, and increase transparency in agriculture. With a blend of theory and real-world applications, it covers everything from AI-driven pesticide prediction and disease identification to using Blockchain for efficient food supply chain management. This comprehensive guide is essential for researchers, professionals, and anyone interested in the intersection of technology and sustainable farming.

Key Features:

- Introduction to Digital Twin technology for sustainable farming

- Practical applications of AI and IoT in agriculture

- Blockchain's role in food supply chain management

- Frameworks for precision agriculture and access to government schemes

- Insights on integrating AI, IoT, and Blockchain into solid waste management systems

In The Generalized Relative Gol‘dberg Order and Type: Some Remarks on Functions of Complex Variables, the authors have discussed the generalized comparative growth analysis of entire functions of several complex variables at length. The discussion covers the important branch of complex analysis specially the theory of analytic functions of several variables. The book contains eight chapters. Chapter 1 presents introductory aspects of the topic and some preliminary definitions. In the proceeding chapters (2-8), the authors derive some results about the generalized Gol'dberg order (α,β) and generalized Gol'dberg type (α,β) of entire functions of several complex variables which progressively explores different variations of these variables, (upper and lower, functions, inequalities, growth measures). The book culminates in an explanation of the sum and product theorems depending on the generalized relative Gol'dberg order (α,β). This monograph is intended for mathematical researchers and enthusiasts who wish to expand their understanding about complex variables of several functions and complex and related aspects of complex analysis.

Tumor development and progression are multi-factorial processes, in which genomic alterations and modifications in gene expression in pre-malignant cells are joined by deleterious microenvironmental factors. The tumor microenvironment contains stroma cells and leukocytes, soluble factors and matrix components. The intensive interplay that exists between the host factors and the tumor cells plays a major role in dictating the final outcome of the malignant process.

Inflammatory mediators are pivotal microenvironmental factors present in the tumor milieu. These inflammatory components support cell growth and invasion, induce mutagenesis, increase angiogenicity, and suppress potential anti-tumor immune functions. The inflammatory constituents that prevail in tumors include leukocytes and soluble mediators - cytokines and chemokines.

This e-book describes the roles played by these mediators in malignancy, and explains the basis for their consideration as therapeutic targets in cancer.

The e-book is a timely overview of the roles played by inflammatory soluble mediators in neoplastic diseases. The topics addressed in this volume serve as a handy reference to investigators studying basic aspects of the malignant tumor growth, to clinicians who wish to better understand the processes involved in malignancy, and to pharmacological professionals seeking novel candidates for therapeutic intervention in cancer.

The field of sleep medicine has gone through tremendous evolution since the discovery of REM sleep in 1953 and remarkable research in recent years has led to multiple advances in sleep medicine. Approvals for new medicines for treating sleep disorders along with new evidence-based interventions for insomnia and sleep apnea, have transformed sleep medicine into a medical specialty in its own right.

The Latest Trends in Sleep Medicine reviews the most important improvements in sleep medicine, with contributions from over fifteen international and respected experts in the discipline. Ten chapters cover topics of interest to healthcare professionals who are focused on somnology such as the management of sleep disorders, restless leg syndrome, sleep apnea medication and surgery, REM sleep behavior disorder and cognitive behavioral therapy for insomnia. In addition to these topics in medicine, the contributors present broader picture of sleep medicine by reviewing secondary topics such as sleep and aging, and driving safety.

The Latest Trends in Sleep Medicine will be useful to healthcare professionals seeking to improve their understanding about contemporary sleep medicine. It also serves as a timely update for respiratory and sleep medicine clinicians, whose efforts are still needed in treating and improving the quality and length of life in patients with complex sleep disorders.

Audience:

Healthcare professionals, residents and students in general, respiratory and sleep medicine sub specialties.

This comprehensive reference is a timely exploration of two vital aspects of triple-negative breast cancer. The book offers a holistic perspective that helps readers to navigate the challenges of managing triple-negative breast cancer (TNBC) with knowledge and confidence.

Understanding Ethnic Disparities and Targeted Therapies: This section provides a critical overview of the ethnic disparities and the latest targeted therapies available for patients facing advanced or metastatic triple-negative breast cancer (TNBC).

Empowering Patients and Enhancing Communication: This section dives into the essential role of patient education, empowerment, effective communication with medical teams, and psychological or supportive approaches, providing invaluable insights into managing advanced or metastatic breast cancer (BC).

Key Features:

Introduces a groundbreaking perspective on the TNBC journey, encouraging patients to view their battle with the disease as an opportunity to leverage modern pharmacological advancements and psychological support for improved outcomes.

Bridges the gap between clinical or research-related aspects of BC management and the personal needs and expectations of patients, promoting a more holistic approach.

Invites perspectives from a wide range of medical professionals, from oncologists and cardiologists to psychologists and nurses, to engage in open dialogues with patients, offering practical education and crucial support.

Provides a wealth of helpful resources (including an appendix) for both patients and their medical caregivers, fostering a comprehensive and supportive approach to managing TNBC.

This book is an informative resource for medical professionals, researchers, and patients, who want to understand the complexities of triple-negative breast cancer and apply current knowledge in their clinical and caregiving practice.