Bentham Science Publishers

Pathways to Green Nanomaterials: Plants as Raw Materials, Reducing Agents and Hosts is a comprehensive guide that explores the fundamental aspects, synthesis methods, and various applications of nanomaterials derived from plants. This book is designed for postgraduate researchers, engineers, and scientists in the fields of materials science, biotechnology, and chemical engineering, as well as other disciplines involved in nanomaterial production and applications.

The book delves into different plant-mediated nanomaterials, analyzing their synthesis mechanisms and discussing the regulation and application prospects of plant synthesis. It covers topics such as nanocellulose, biochar materials, plant exosomes, polyphenol nanoparticles, and the phytotoxicity and uptake of nanomaterials by plants. Additionally, it explores the research progress and applications of plant virus nanoparticles in the medical field, including drug delivery, molecular imaging, and vaccine preparation. Readers will be familiarized with the synthetic methods, characterization, and applications of green nanomaterials, paving the way for future studies on plants and their phytochemical constituents.

With its comprehensive coverage of plant-derived nanomaterials and their diverse applications, Pathways to Green Nanomaterials: Plants as Raw Materials, Reducing Agents and Hosts serves as a valuable resource for researchers seeking to understand the potential of plants as sustainable sources for nanomaterial production.

Pediatric Anesthesia: A Guide for the Non-Pediatric Anesthesia is a comprehensive, contemporary reference that addresses all aspects of pediatric anesthesia. Both students and medical practitioners - novice and experienced - will find invaluable educational and practical information in this book. The book covers the subject in two parts.

Part I covers basic information about pediatric and neonatal anatomy and physiology, pharmacology, emergency room and operating room procedures and surgery. Chapters on general anesthetic procedures in emergency rooms, operational theatres and common surgeries.

Part II covers advanced topics for practicing healthcare professionals which include anesthesia for patients with a range of common and uncommon comorbidities, considerations for critically-ill patients, genetic disorders, pain management, COVID-19 guidelines for anesthesia, patient safety and research.

Key features:

- Basic and advanced information about pediatric and neonatal anesthesia covered in 25 chapters over two parts

- Simple and organized presentation for learners

- Contributions by expert clinicians and researchers

- Special topics included such as considerations for patients with comorbidities and genetic disorders

- References for further reading

- Detailed illustrations and tables

The text is an essential reference for scholars and professionals affiliated with general anesthesiology and surgery specialties at all levels who want to understand anesthesia for pediatric patients.

This book explores a variety of topics that fall in the realm of psychological and behavioral economics. It demonstrates to the reader how to perform straightforward experiments in order to understand how people think about the economic aspects of their daily lives.

Behavioral economics is a 'hot new area' of economics and consumer psychology. This book provides a comprehensive guide on consumer research and the types of results required. These approaches are spreading further around the globe, thanks to the work of Dr. Howard Moskowitz, one of the authors of this book, and the incredible success of Selling Blue Elephants. In other words, the book is just slightly ahead of a sea change in consumer research, and may be one of the 'tipping points'. (Coincidentally, Malcolm Gladwell, the bestselling author, is a great admirer of Dr. Moskowitz)

In Perinatal Cardiology, fetal cardiology experts provide key information on tools for fetal evaluation through echocardiography / cardiac ultrasonography, with a primary focus on the nature and prenatal detection of structural and functional cardiac heart defects (CHDs). In this two-part book, readers will find details about different types of fetal cardiac abnormalities along with important updates on the diagnosis, management, planning delivery, and postnatal treatment in CHD cases. This information is supplemented with guidelines for the clinical management of patients with a fetus affected by cardiovascular defects, and surgical procedures in neonates.

Key Features:

-presents information gathered by experts in perinatal cardiology, organized into 26 topic-based chapters

- explores the cardiac development, fetal cardiovascular hemodynamics, genetic and environmental factors associated with congenital heart defects (CHD), perinatal management, planning delivery, and postnatal treatment of newborns with CHD

- presents information about normal cardiac functions and heart defects to give readers a clear and detailed picture of abnormal cardiac function

- presents information about perinatal ultrasound physiology

- gives practical guidelines for ultrasound and echography parameters required for evaluating fetal heart anatomy and diagnosing diseases

- includes a new system of classifying prenatal CHDs based on the stratification of the risk level of care

- features a straightforward and accessible style of presentation suitable for all readers

- provides references in each chapter for further reading

Part 1 of this two-part set covers the basics of perinatal cardiology which chapters that introduce readers to CHD classification, fetal heart and placental physiology and pathology, diagnosis of fetal cardiac malposition and anomalies and some congenital heart defects such as septal defects, cardiac anomalies of the left and right sides, conotruncal anomalies and aortic arch anomalies.

Perinatal Cardiology is an essential reference for postgraduate medical students seeking to improve their knowledge of fetal and pediatric cardiology as part of their residency and professional training. The book equips readers with the information necessary to understand the role of the perinatal cardiologist and goes further to facilitate the ability to perform adequate risk assessments for fetal CHD.

This book introduces personalized immunotherapy with multi-dimensional models of analysis to determine the best plan for immunotherapy of patients. The book introduces readers to some basic concepts which lay the foundation for personalized immunotherapy: the development of a major histocompatibility complex (MHC), the genome profile of T cells and tumor cells, and genome-wide association studies. Chapters also cover special topics such as new immunoassay methods related to personalized immunotherapy and targeted immunotherapy which are geared towards familiarizing readers with current research practices. Focusing on the central theme of personalized immunotherapy, the authors provide a wealth of information about T-cell screening, tumor neoantigen cloning, primary tumor cell culture for T-cell cloning, bioinformatics strategies for understanding T-cell and primary tumor cell biology and function, and new developments in research on adoptive T-cell immunotherapy. These developments include T-cell gene therapy and T-cell gene editing, transgenic T-cells for increasing affinity to tumor cells such as CAR T-cells and TCR T-cells, and the systematic modeling of polyclonal specific T-cells and biobank technology.

Key Features:

- Introduces readers to basic concepts in personalized medicine and immunotherapy

- Presents current information about immunological assays used in research

- Presents an overview of T cell immunotherapy and cloning techniques

- Presents an overview of tumor cell bioinformatics and its role in immunotherapy

- Includes new developments and references for personalized immunotherapy techniques (T-cell gene therapy and T-cell gene editing, transgenic T-cells which target CAR T-cells and TCR T-cells, and polyclonal T-cell modeling)

- Includes a section on biobanking

- Presents information in an easy-to-read format for a wide range of readers

- Brings contributions from experts with over 30 years of experience in personalized immunotherapy

Personalized Immunotherapy for Tumor Diseases and Beyond is an ideal handbook for medical professionals and students involved in personalized medicine, immunology and oncology. General readers interested in the new developments in these fields will also benefit from the information provided.

This textbook summarizes preliminary knowledge of bioactive molecules which serve as pharmaceuticals, their use, synthesis and mode of action, as well as the production of commercial constituents such as ethanol, citric acid, antibiotics, amino acid, and vitamins.

The text is written mainly for the undergraduate and graduate levels of study of all Indian universities according to the recently implemented CBCS curriculum in a simple manner while keeping postgraduate course structures in view.

Key Features:

Simple structured layout suitable for learners

- Considers the CBCS curriculum for Indian Institutions

- Covers the subject in 2 parts (Part A: Pharmaceutical Chemistry, Part B: Production)

- Covers several types of pharmaceuticals used in clinical practice

- Covers the fermentation process and the production of antibiotics, pharmaceutical commodities, and nutrients

- Includes an appendix for handy information

This reference summarizes information about pharmaceuticals that can target infectious strains of coronaviruses to neutralize infections. Chapters focus on SARS-CoV-2, drug discovery methods and natural methods to combat the virus, which is a causative agent of COVID-19.

Specifically, the book presents 5 chapters written by expert scholar on the following topics:

Structure-Based Drug Discovery Approaches Applied to SARS-CoV-2 (the causative agent COVID- 19)

Potential Antiviral Medicinal Plants against Novel SARS-CoV-2

Infections Caused by SARS Coronaviruses:

Main Characteristics, Targets and Inhibitors Natural Sourced Traditional Indian and Chinese Medicines to Combat COVID- 19

Peptidomimetic and Peptide-Derived Agents Against 3CLpro from Coronaviruses The book contents present both conventional drug design and traditional approaches to discovering relevant drugs in an easy-to-read approach, which is supplemented by bibliographic references. It is intended as a reference for students (pharmacology, pharmacy) and researchers (virology) who are seeking information about antiviral drugs that can be used against coronaviruses.

Pharmacological and Molecular Perspectives on Diabetes is a compilation of reviews on clinical and scientific aspects of diabetes mellitus. It presents 11 contributions by eminent scholars that give the reader rational pharmacological and genetic perspectives of the disease and its treatment. The reviews approach diabetes from different angles, and highlight research that has been done to understand some questions about the molecular biology of diabetes in experimental settings. Topics of clinical significance such as the use of different hypoglycemic agents, and diabetic complications in clinical settings are also covered.

Topics included in this book are:

- Epigenetic alterations and type 2 diabetes mellitus

- Responses to nutritional chromium supplements for type 2 diabetes mellitus

- Endocrine role of osteocalcin in homeostatic regulation of glucose metabolism

- Effect of diabetes on memory

- Osteoarthritis in relation to type 2 diabetes mellitus: prevalence, etiology, symptoms and molecular mechanism

- Infection of novel coronavirus in patients with diabetes mellitus

- Role of an anti-inflammatory agent in the management of type 2 diabetes mellitus

- Role of antidiabetic agents which helps regulates TCF7L2 variations in type 2 diabetes mellitus

- Relationship between type 2 diabetes mellitus, PCOD and neurological disorders: role of antidiabetic drugs Comparison of different types of insulin available for type 1 diabetes treatment

- Circadian rhythm disruption: special reference to type 2 diabetes mellitus

- Type 2 diabetes mellitus and its complications: pharmacogenetics based correlations and circulating microRNA as biomarkers Pharmacological and Molecular Perspectives on Diabetes should prove to be of interest to all pharmaceutical and molecular biology scientists who are involved in research in anti-diabetic drug design and discovery, and practicing endocrinologists who wish to keep abreast of recent developments in the field.

Pharmacotherapeutic Management of Cardiovascular Disease Complications is an essential textbook that comprehensively informs the reader about a broad variety of cardiovascular pathologies and their management through drug therapy.

Key Features:

- Features 22 chapters, with 17 chapters dedicated to the management of a wide range of cardiomyopathies and related complications

- Introduces readers to heart anatomy and physiology, for both medical and pharmacology students

- Covers information on cardiovascular disease biomarkers as well as current and new technologies for diagnostic procedures

- Provides additional information on different aspects of cardiovascular disease treatment including etiological factors, prevalence, pathogenesis, clinical symptoms, diagnosis and prevention factors, risk screening and complications

- Informs readers on the role of the clinical pharmacist in patient lifestyle modification for therapeutic plans, helping to reduce cardiovascular disease burden in clinical practice

The broad coverage and easy-to-read organization of the topics covered on the subject make this textbook an ideal reference for medical students and health care professionals such as doctors, nurses, clinical pharmacists, community pharmacists and paramedics.

Phosphorylated Extracellular Matrix Proteins of Bone and Dentin is the second volume of the e-book series Frontiers between Science and Clinic in Odontology. The phosphorylated proteins of the extracellular matrix of bone and teeth play a crucial structural role in the two tissues. They also act as signaling molecules. Phosphorylated extracellular matrix proteins have been implicated in nucleation and mineralization of skeletal tissues. This e-book covers research on these specific proteins, including details about the cells producing these molecules, their impact on bone and teeth pathology (osteogenesis and dentinogenesis imperfecta) and the potential of these molecules in promoting of inhibiting mineralization.

This e-book also explains processes under the control of some enzymes - TNAP and metalloproteases (MMPs) - such as intracellular regulation in bone and dentine, splicing, respective roles of cleavage products, SIBLINGs, nucleation and crystal growth and regulation.

This second volume serves as a valuable reference to practicing odontologists, biology and biomaterials scientists and tissue engineers interested in protein research related to tooth and bone formation.