Bentham Science Publishers

Rheumatoid arthritis (RA) is the most common inflammatory complication and affects approximately 1 % of the global population. It affects three times more women than men. RA is an autoimmune disorder elicited by exposure of genetic factors from the host to unknown antigens causing arthritogenic complaints. It also includes the activation of lymphocytes as well as CD4+ helper T cells along with the local release of chronic inflammatory mediators and cytokines like tumor necrosis factor (TNF-α) and various cytokines like interleukins (IL) that enormously affect the joints. The available allopathic therapies for RA are not a cure for the complications, and antibody therapy and surgical procedures are expensive.

However, in the present era, researchers and healthcare professionals have moved toward natural medicines obtained from plants and other natural sources. Research-based on developments in phytomedicine has progressed steadily. Evidence has been collected to show the massive therapeutic potential of medicinal plants used in various traditional systems against many pathological complications. Researchers have focused on the therapeutic potential of natural products used for treatment and counteracting various disorders along with their complications having negligible adverse effects.

Natural Products for the Management of Arthritic Disorders compiles current knowledge about the bioactive compounds and herbal formulations useful in the treatment of rheumatoid arthritis. 11 chapters explain the role of natural products in the management of rheumatoid arthritis. Topics have been contributed by experts in medicinal chemistry and rheumatology.

The book first introduces the reader to rheumatoid arthritis before delving into conventional and alternative therapies for the disease. The editors have also included special topics such as the biomarkers for RA, cytokines and anti-inflammatory mediators, and preclinical and clinical studies. The range of topics should provide a comprehensive overview of natural remedies for arthritis and the role of natural products in anti-arthritic drug development.

The information will be useful for many readers including medical and pharmacology students, multidisciplinary research scholars, scientists, pharma/herbal/food industrialists, and policy makers.

Natural compounds continue to play a key role in drug development. Many clinically approved drugs are either unmodified natural products or their semi-synthetic derivatives. This book series presents reviews of exciting new bioactive natural products that have huge potential as drugs. Each volume presents comprehensive chapters contributed by eminent scientists. The volumes focus on drug candidates which are in the later stages of drug development and are being evaluated in clinical trials. The series, therefore, highlights the importance of natural products in our lives.

The second volume covers the following topics:

- A review of recent patents and natural products in clinical trials to treat schistosomiasis

- Natural products: the new intervention regimen for metabolic disorders

- Fluorine-containing drugs and drug candidates derived from natural products

- Natural products for the management of cardiovascular diseases

- Implication of natural compounds for the prevention of ocular diseases

A comprehensive and practice-oriented exploration of blockchain technology, tracing its evolution from Bitcoin to Ethereum and beyond. This volume explains blockchain's foundational principles, such as decentralization, immutability, and cryptographic security, before moving into real-world applications across finance, supply chain management, healthcare, governance, and emerging tech ecosystems.

With contributions from leading researchers and practitioners, the book examines both opportunities and challenges ranging from scalability and energy consumption to regulatory clarity and security. Readers also gain insights into cutting-edge developments like smart contracts, decentralized finance (DeFi), identity systems, Layer 2 solutions, DAOs, and blockchain's synergy with IoT and AI.

Key Features

Explains the core principles of blockchain, from decentralization to cryptographic security.

Traces the evolution from Bitcoin and Ethereum to DeFi, smart contracts, and dApps.

Demonstrates applications across finance, healthcare, supply chain, governance, and identity management.

Addresses pressing challenges, including scalability, energy use, regulatory frameworks, and security threats.

Explores future trends like interoperability, DAOs, Layer 2 solutions, and integration with IoT and AI.

Navigating through Technology in Modern Education explores the transformative impact of digital innovation in education. From introducing digital transformation to discussing the benefits and challenges, this book covers crucial topics like e-learning, artificial intelligence, big data, and the Internet of Things in education. With insights into factors for adopting technology and tailored learning experiences, this book equips readers with the knowledge to navigate the evolving landscape of modern education. Whether you're a seasoned educator or a newcomer, this book offers valuable insights into leveraging technology for enhanced learning experiences.

Agent technology has generated lots of excitement in the past decade. Currently, multi-agent systems (MAS) composed of autonomous agents representing individuals or organizations and capable of reaching mutually beneficial agreements through negotiation and argumentation are becoming increasingly important and pervasive.

Research on both automated negotiation and argumentation in MAS has a vigorous, exciting tradition. However, efforts to integrate both areas have received only selective attention in the academia and the practitioner literature. A symbiotic relationship could significantly strengthen each area's progress and trigger new R&D challenges and prospects toward the advancement of automated negotiators and argumentation tools.

Negotiation and Argumentation in Multi-Agent Systems presents the current state-of-the-art on the theory and practice of automated negotiation and argumentation in MAS. The eBook encourages the interaction between these two areas in data modelling and attempts to converge them toward mutual enhancement and synergism. Equally, the monograph brings together researchers and industry practitioners specialized in these areas to share R&D results and discuss existing and emerging theoretical and applied problems.

This book is intended as a textbook for graduate courses and a reference book for researchers, advanced-level students in Computers Science, and IT practitioners.

Clinical chemistry is a science that requires specific knowledge and teaching. The e-book covers several topics in clinical nephrology. Patients suffering from severe chronic kidney disease may be quasi asymptomatic. This lack of overt symptomatology suggests that clinical laboratory tests are of the highest importance. Clinicians treating patients and clinical biologists operating in laboratories are often far apart from each other. They have a lot of things to share and to learn from each other. This e-book bridges the gap between these two groups of health professionals.

This book dives into the heart of how to design distributed control architectures for heterogeneous teams of humans, robots, and automated systems, enabling them to achieve greater cooperation and autonomy through the use of network technologies. It provides a wide range of practical, proven strategies for pervasive communication and collaborative problem solving abilities of humans, robots, and their environments. Each chapter consists of a presentation of findings from the latest research in networked robots and ambient intelligence. The chapters also detail how to allow robots to achieve universal access to the extended functionality of the environment that brings various cost effective services to those in need. Readers can envision a realistic view of what can be expected from a networked human robot cooperative environment in the next decade.

This monograph is a collection of selected articles on the subject of mood disorders such as depression and schizophrenia. It is divided into 3 sections: 1) Research methods in psychopharmacology - which highlights some established experimental techniques to study mood disorders in human and relevant animal models, 2) Pathophysiology of mood disorders – which explains the physiological and pharmacological mechanisms responsible for mood disorders and 3) New strategies for the treatment of mood disorders – a concluding section that provides recent examples on the beneficial effects of pharmacological and non-pharmacological interventions in the relief of mood disorders. The e-book serves as a primer for graduate students and researchers interested in the physiology and treatment of affective psychological disorders.

NBE is the official journal of the Institute of Complex Medical Engineering (ICME). The journal promotes the best interdisciplinary research in neuroscience and biomedical engineering. NBE welcomes contributions in any domain of neural and biomedical engineering ranging in content from practical/clinical applications through experimental science, technological developments to quantitative and/or statistical methodology discussions. NBE publishes the following article types: original articles, research reviews, and book reviews.

The goal of this journal is to establish a new forum for this interdisciplinary field so neuroscientists and biomedical engineers can publish their research works in one periodical. NBE is devoted to bridge the gap between Neuroscience and Biomedical Engineering , and to foster the mutual understanding in both fields.

Typical topics include, but certainly are not limited, to the following:
Neural Technology and Neural Rehabilitation
Neurology and Signal Processing
Biomedical Informatics
Biomechanics and Neural Control
Theoretical and Computational Neuroscience
Imaging Neuroscience

Key Features:

- Original research papers and special issues for topics
- Basic neurosciences, and biomedical engineering technologies
- Existing and potential clinical applications
- Periodic ‘Review Papers’ from world-recognized experts
- International scope
- No page charges
- Rapid publication times
- Free color in electronic version

Increasingly global and online social interactions and financial transactions involve digital data, computing devices and the internet. With cloud computing, remote computing, enterprise mobility and e-commerce on the rise, network security has become a priority. Selecting an appropriate algorithm and policy is a challenge for computer security engineers, as new technologies provide malicious users with opportunities to intrude into computer networks.

New Age Cyber Threat Mitigation for Cloud Computing Networks provides cloud and network engineers answers to cybersecurity challenges. It highlights new options, methodologies and feasible solutions that can be implemented in cloud architecture and IT Infrastructure, thereby securing end users. Chapters cover many topics related to cyber threats in the modern era.

These topics include:

Ransomware and DDoS attacks

Security algorithms

Design and implementation solutions for resilient and fault-tolerant cloud and network services

Security policy

End user data security The book is an essential resource for anyone involved in cloud computing and network security, including learners, professionals and enthusiasts.