Bentham Science Publishers

Recent Advances in Medicinal Chemistry is a book series focused on leading-edge research on developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The series presents highly cited contributions first published in the impact factor journal Mini-Reviews in Medicinal Chemistry. Contributors to this volume have updated their work with new experimental data and references following their initial research. Each volume highlights a number of important topics in current research in medicinal chemistry.

Selected chapters in this volume include:

- A brief review of polyphenols as phytotherapeutic agents

- Flavonoids in foods and biological samples

- Cannabinoid use in treating Parkinson's Disease symptoms

… And much more.

The present Ebook deals with various strategies that have frequently been followed to fabricate nanostructures of required size and shape, and with required functionalities to enable them to be used in a wide spectrum of industrial, biomedical and technological applications. This Ebook presents unique novel methodologies of synthesis of nanoparticles by various means.

While the world is grappling with the growing problem of antibiotic resistance, marine organisms offer a promising solution with their diverse repertoire of bioactive compounds. This thematic volume explores the untapped potential of marine organisms in the fight against microbial threats. The focus of the 17 featured chapters lies in highlighting the vast array of antimicrobial agents that can be found within marine environments. The chapters provide in-depth knowledge about the latest discoveries, advancements and future needs in antimicrobial research. Readers will learn about astonishing discoveries of natural compounds with remarkable antimicrobial properties and sources. The list of agents covered in the book includes synthetic derivatives, bioactive polysaccharides and marine viruses. The book also includes chapters that cover various stages of the antimicrobial drug development process, providing an overview of recent antimicrobial agents derived from marine organisms, preclinical studies and the identification of patented drugs sourced from the ocean. Furthermore, the book sheds light on the diverse applications of these marine-derived compounds, spanning the fields of medicine, agriculture, and industry.

Professionals in the fields of microbiology, marine biology, pharmaceutical sciences, and drug development will gain valuable insights into the use of marine organisms as a source of antimicrobial agents.

Researchers have tried various effective treatments that prevent the progressive neurodegeneration of neurons within the brain. Parkinson's disease (PD), Alzheimer's disease (AD), and Multiple sclerosis (MS) are some of the most common neurodegenerative diseases (NDDs). Recent Advances in the Treatment of Neurodegenerative Disorders provides interesting updates on treatments of these neurological disorders. Ten chapters have been contributed by experts in pharmacology and give a unique perspective to reader on special topics in this area, including the treatment of neurodegenerative treatment of neurodegenerative disease through ayurveda and phytochemicals, the therapeutic role of vitamins in Parkinson's disease, mushrooms in NDD treatment, MS treatment, ALS treatment and the use of nanoparticles and nano formulations in NDD treatment. This is an informative reference for pharmacologists, medicinal chemists and healthcare professionals (general practitioners and neurologists) seeking updates in the treatment of some common neurodegenerative disorders.

This book is an updated reference of research activities that bring together various theories, methods, and technologies of robotic systems and automation for manufacturing and related fields. The book includes articles on state-of-the-art robotic systems and automation for diverse avenues in automation such as advanced manufacturing, developments in design methodology, kinematics and dynamics analysis, performance analysis and evaluation, intelligent manufacturing, assembly, sensors, control theory and practice, human-machine interface, and so on. This book is an excellent research reference for engineers, researchers, and students that range from senior undergraduates to advanced doctoral students and professionals who are interested in robotics and automation.

Recent Progress in Pharmaceutical Nanobiotechnology: A Medical Perspective offers a comprehensive exploration of the dynamic field of pharmaceutical nanobiotechnology, focusing on its medical applications. This edited reference serves as a valuable resource for researchers, students, and professionals in various disciplines (pharmacology, biotechnology, clinical medicine and nanotechnology) , providing insights into the latest advancements and practical implications of nanotechnology in the pharmaceutical sector.

The book presents 14 edited and referenced chapters that cover several themes for readers.

General Pharmaceutical Nanobiotechnology:

Introduction to the interdisciplinary field

Exploration of nanoscale materials for medical purposes

Nanoparticle Development and Applications:

Bioinspired Nanomedicines

Lipid-Based Nanocarriers

Metallic Nanoparticles and Their Applications

Nanoparticle Targeting Strategies

Nanomedicine-Based Therapies for Cancer Stem Cells

Biotechnological Aspects:

Biotechnological Significance of Exosomes

Glycoconjugates: Biosynthesis and Functions

Innovative Nanotherapies:

Novel Nanotechnological Approaches for Glioblastoma

Biocompatibility of Nanomedicines and Bio Corona

Diagnostic and Sensing Applications:

Role of Nanoparticular/Nano Vesicular Systems as Biosensors

In Vitro Applications of Drug-Carrying Nanoparticles in Cell Culture Studies

In Vivo Imaging Techniques: Bioluminescence and Fluorescence Imaging

Precision Medicine:

The Role of Nano and Biopharmaceutics in Precision Medicine

"Recent Technologies in the capture of CO2" provides a comprehensive summary on the latest technologies available to minimize the emission of CO2 from large point sources like fossil-fuel power plants or industrial facilities. This ebook also covers various techniques that could be developed to reduce the amount of CO2 released into the atmosphere.

The contents of this book include chapters on oxy-fuel combustion in fluidized beds, gas separation membrane used in post-combustion capture, minimizing energy consumption in CO2 capture processes through process integration, characterization and application of structured packing for CO2 capture, calcium looping technology for CO2 capture and many more.

Recent Technologies in capture of CO2 is a valuable resource for graduate students, process engineers and administrative staff looking for real-case analysis of pilot plants. This eBook brings together the research results and professional experiences of the most renowned work groups in the CO2 capture field.

This book integrates knowledge about innovative technologies developed in the past decade with information about commercial-scale processes. It is written with the objective to help readers to understand the potential of achieving sustainability and high efficiency in wastewater treatment. The book presents nine chapters. Chapter 1 details the types of wastewater, its characteristics, and the major commercial-scale strategies employed to treat wastewater. Chapter 2 details the different types of physicochemical methods utilized for the remediation of heavy metals, dyes, and xenobiotics. Chapters 3 and 4 highlight innovations in the advanced oxidation process and adsorption for remediation of such complex molecules, respectively. Chapters 5, 6, and 7 highlight the recent innovations in bioremediation of xenobiotics, heavy metals, and dyes, respectively. Finally, chapters 8 and 9 discuss the latest technologies, prevailing bottlenecks, and the path ahead towards commercial viability and environmental sustainability in both physico-chemical and biological treatment processes.

Recent Trends and the Future of Antimicrobial Agents provides a significantly expanded overview of the topic with updated research in a broader context on the development of alternative approaches against microbial infections.

This part primarily describes the use of probiotics, chemically synthesized compounds and nanomaterials as antimicrobial agents. The first chapter describes the potential of probiotics for the restoration of gut microbiomes. Amongst various antimicrobial agents, the use of antibodies has recently been investigated as a potential remedy. A chapter on antibody-based therapy as an alternative to antibiotics has been included. Chemical synthesis has eased the development of target-based prospective drug molecules against microorganisms. Chemically synthesized cationic amphiphiles and amphiphilic nanocarriers as antimicrobial agents have been discussed with sufficient detail in two different chapters. Research and progress in Schiff Base-Metal Complexes and Metal-Organic Frameworks for their antimicrobial applications have also been described in two separate chapters. Independent chapters discussing the design, synthesis and antimicrobial applications of biogenic metal or metalloid nanoparticles, bactericidal QDs and MoS2-based antibacterial nanocomposites have fulfilled the aim of incorporating cutting-edge research in the areas of alternative antimicrobials. Also, a new-age approach to combat microbes, antimicrobial photodynamic therapy (aPDT), is discussed in the final chapter of the edited volume. This part intends to provide the readers with an updated and broad view of research and development in alternative remedial approaches against microbial infections.

The contents cater to the information needs of professionals and learners in academia, industry and health services who aim to learn the most significant experimental and practical approaches towards finding alternatives to existing antimicrobial therapies.

In a constantly changing economic environment, higher education institutions need to adapt in order to be relevant to their stakeholders and the society. The unpredictable landscape also demands a fresh approach as university presidents are increasingly subject to high resolution and three-dimensional scrutiny. Instead of relying on last century’s old management mindset, university leaders must build institutions that are agile and flexible, which can continuously learn to adapt to the changing environment. Redefining University Leadership for the 21st Century is a treatise on the challenges universities face in current times. Readers will understand, in three parts, the heart of what makes a great university.

The initial part of the book covers the market failures and the management practices that have led to the erosion of confidence in universities among stakeholders. The authors examine the consequences of market failures caused by the marketization of higher education: an oversupply of graduates, student dissatisfaction, mismatch between qualifications and needed skills, student disillusionment, and the diminishing return on investments by students and their families.

Next, authors offer concrete advice on how universities can future-proof university graduates in this fast-changing world of the fourth industrial revolution and artificial intelligence. The authors also provide valuable strategies to help university leaders to lead effectively in this uncertain world with a concluding case study on the University of Hong Kong.

With its clear, logical and concise presentation, Redefining University Leadership for the 21st Century is a must-read for anyone who leads, works or studies in a university, or is interested in current trends in the higher education sector.

Refounding Political Governance: The Metaphysics of Public Administration points to a possible paradigm shift in the way Anglo-American Public Administration should be understood and analyzed. The book presents a unique approach to the analysis of power, leadership and management in Public Administration. The central theme is that humans make organizations in their own image and these organizations, in turn, are a product of the way humans think and act. The book extrapolates from historical philosophy and personality typologies to explain the dynamics and evolution of Public Administration. With the philosophical framework and approach clearly explained, the book provides a critique of current practice and recommends what is required to re-invent Public Administration, rather than New Public Management, in Anglo-American contexts.

The book explains a new, more complex, and more useful, understanding of the dynamics of contemporary US Public Administration situated within the American Constitution. This book is ground-breaking and should be useful in all graduate Public Administration courses and professionals in the field of Public Administration.