Bentham Science Publishers

Designing and developing new drugs is an expensive and time-consuming process, and there is a need to discover new tools or approaches that can optimize this process. Applied Computer-Aided Drug Design: Models and Methods compiles information about the main advances in computational tools for discovering new drugs in a simple and accessible language for academic students to early career researchers. The book aims to help readers understand how to discover molecules with therapeutic potential by bringing essential information about the subject into one volume. Key Features . Presents the concepts and evolution of classical techniques, up to the use of modern methods based on computational chemistry in accessible format. . Gives a primer on structure- and ligand-based drug design and their predictive capacity to discover new drugs. . Explains theoretical fundamentals and applications of computer-aided drug design. . Focuses on a range of applications of the computations tools, such as molecular docking; molecular dynamics simulations; homology modeling, pharmacophore modeling, quantitative structure-activity relationships (QSAR), density functional theory (DFT), fragment-based drug design (FBDD), and free energy perturbation (FEP). . Includes scientific reference for advanced readers

This book provides an ideal foundation for readers to understand the application of artificial intelligence (AI) and machine learning (ML) techniques to expert systems in the healthcare sector. It starts with an introduction to the topic and presents chapters which progressively explain decision-making theory that helps solve problems which have multiple criteria that can affect the outcome of a decision. Key aspects of the subject such as machine learning in healthcare, prediction techniques, mathematical models and classification of healthcare problems are included along with chapters which delve in to advanced topics on data science (deep-learning, artificial neural networks, etc.) and practical examples (influenza epidemiology and retinoblastoma treatment analysis).

Key Features:

- Introduces readers to the basics of AI and ML in expert systems for healthcare

- Focuses on a problem solving approach to the topic

- Provides information on relevant decision-making theory and data science used in the healthcare industry

- Includes practical applications of AI and ML for advanced readers

- Includes bibliographic references for further reading

The reference is an accessible source of knowledge on multi-criteria decision-support systems in healthcare for medical consultants, healthcare policy makers, researchers in the field of medical biotechnology, oncology and pharmaceutical research and development.

Architecture in Contemporary Literature artfully weaves the tapestry of architecture with the eloquence of modern literary masterpieces. In this follow up to their earlier work on architecture in fictional literature, the editors have carefully selected 31 significant works from contemporary world literature, offering a fresh educational approach to literary critique and architecture. This exploration allows readers to perceive life through the lens of architectural backgrounds. Nature, society, humans, and cities come to life through these chosen literary gems. Extensive collaboration with architects, intellectuals, academics, writers, and thinkers culminates in the selection of influential works that guide present-day architectural perspectives and aspirations.

The book promises to be a valuable reference for undergraduate and graduate students in architecture, interior architecture, urban planning, fine arts, humanities, social sciences, and various design disciplines. Yet, its appeal also extends to anyone with an appreciation for urban life and a desire for a broader understanding of the intricacies of architecture. Whether you're an expert in design, culture, art, sociology, or literature, or simply an avid learner, Architecture in Contemporary Literature is a compelling exploration that deserves a prominent place on your bookshelf. Engage with its pages and immerse yourself in the fusion of architectural insight and literary artistry.

This book provides a single platform for beginners in systems engineering to start Arduino interface projects with MATLAB®. It covers the basics of the programming with Arduino and Arduino interfacing with MATLAB® (with and without the use or I/O packages) in 3 sections, respectively.

Key features:

-introduces readers to Arduino IDE, Proteus simulation modeling, Arduino interfaces with display devices, sensor interfaces (both digital and analog), actuators, MATLAB® GUIs, digital read/write systems with I/O interfaces and automation systems.

-organized layout for a reader friendly experience

-provides detailed circuit diagrams

-provides relevant simulation modeling instructions

This is an ideal book for engineering students and system designers for learning the basic programming and simulation of Arduino and MATLAB® based real time project prototypes.

Arid and Semi-Arid Zones of Mexico: A Comprehensive Exploration of Biodiversity, Ecology, and Conservation is an in-depth, multidisciplinary examination of one of Mexico's most ecologically distinctive and biologically rich landscapes. Comprising 14 chapters authored by subject-matter experts, this reference work investigates the climatic, physical, and biological characteristics of Mexico's principal arid and semi-arid regions.

The volume presents detailed assessments of emblematic plant and animal species, while also exploring the ecological roles of nursery processes and the consequences of human activity on fragile desert ecosystems. Conservation priorities are addressed through evaluations of protected natural areas and the safeguarding of native germplasm resources. Additionally, the contributors document the medicinal and biologically active products derived from arid-zone flora, highlighting their ecological and cultural significance.

Each chapter integrates case studies and findings from Mexico's key arid regions — the Baja California Peninsula, Chihuahuan Desert, Sonoran Desert, and Tehuacán-Cuicatlán Valley.

Key Features

Comprehensive ecological, biological, and conservation analysis of Mexico's arid and semi-arid regions

In-depth focus on emblematic fauna and flora

Examination of ecological processes, human impacts, and conservation strategies

Assessment of protected areas and germplasm conservation efforts using cacti as umbrella taxa

Documentation of natural products with medicinal and biological applications

Integrative analyses across four major arid regions, highlighting ecological patterns and biodiversity trends

This book is a personal, political and philosophical exploration of doing both therapy and research: an enquiry into how the process of therapy shapes the therapist as well as the client, and how the researcher is shaped by her research. A guiding theme is the proposal, following Foucault and Nikolas Rose, that psychotherapy is constituted, through forms of modern power, as a crucial contemporary site of both governance and resistance. As well as giving an account of the author's clinical and research practices as an art psychotherapist and narrative therapist, the book offers a highly readable introduction to poststructural theory and innovative social sciences methodologies, while expanding the understanding and practice of these theories and methodologies. The book embodies and performs what it describes, engaging readers far more strongly in complex theoretical material than is possible in an expository text. The poststructural, autoethnographic approach taken in this book is unique in the field of the arts therapies.

Artificial Intelligence Development in Sensors and Computer Vision for Health Care and Automation Application explores the power of artificial intelligence (AI) in advancing sensor technologies and computer vision for healthcare and automation. Covering both machine learning (ML) and deep learning (DL) techniques, the book demonstrates how AI optimizes prediction, classification, and data visualization through sensors like IMU, Lidar, and Radar. Early chapters examine AI applications in object detection, self-driving vehicles, human activity recognition, and robot automation, featuring reinforcement learning and simultaneous localization and mapping (SLAM) for autonomous systems. The book also addresses computer vision techniques in healthcare and automotive fields, including human pose estimation for rehabilitation and ML in augmented reality (AR) for automotive design. This comprehensive guide provides essential insights for researchers, engineers, and professionals in AI, robotics, and sensor technology.

Key Features:

- In-depth coverage of AI-driven sensor innovations for healthcare and automation.

- Applications of SLAM and reinforcement learning in autonomous systems.

- Use of computer vision in rehabilitation and vehicle automation.

- Techniques for managing prediction uncertainty in AI models.

Artificial Intelligence and Data Science in Recommendation System: Current Trends, Technologies and Applications captures the state of the art in usage of artificial intelligence in different types of recommendation systems and predictive analysis. The book provides guidelines and case studies for application of artificial intelligence in recommendation from expert researchers and practitioners. A detailed analysis of the relevant theoretical and practical aspects, current trends and future directions is presented.

The book highlights many use cases for recommendation systems:

- Basic application of machine learning and deep learning in recommendation process and the evaluation metrics

- Machine learning techniques for text mining and spam email filtering considering the perspective of Industry 4.0

- Tensor factorization in different types of recommendation system

- Ranking framework and topic modeling to recommend author specialization based on content

- Movie recommendation systems - Point of interest recommendations

- Mobile tourism recommendation systems for visually disabled persons

- Automation of fashion retail outlets

- Human resource management (employee assessment and interview screening)

This reference is essential reading for students, faculty members, researchers and industry professionals seeking insight into the working and design of recommendation systems.

This book explains different applications of supervised and unsupervised data engineering for working with multimedia objects. Throughout this book, the contributors highlight the use of Artificial Intelligence-based soft computing and machine techniques in the field of medical diagnosis, biometrics, networking, automation in vehicle manufacturing, data science and automation in electronics industries. The book presents seven chapters which present use-cases for AI engineering that can be applied in many fields. The book concludes with a final chapter that summarizes emerging AI trends in intelligent and interactive multimedia systems. Key features: - A concise yet diverse range of AI applications for multimedia data engineering - Covers both supervised and unsupervised machine learning techniques - Summarizes emerging AI trends in data engineering - Simple structured chapters for quick reference and easy understanding - References for advanced readers This book is a primary reference for data science and engineering students, researchers and academicians who need a quick and practical understanding of AI supplications in multimedia analysis for undertaking or designing courses. It also serves as a secondary reference for IT and AI engineers and enthusiasts who want to grasp advanced applications of the basic machine learning techniques in everyday applications.

Smart cities and villages have enhanced the quality of lives of residents. Various computer-assisted technologies have been harnessed for the development of smart cities and villages in order to provide solutions for common and niche urban problems. The development of smart environments has been possible due on advances in computing power and artificial intelligence (AI) that have allowed the deployment of scalable technologies.

Artificial Intelligence for Smart Cities and Villages: Advanced Technologies, Development, and Challenges summarizes the role of AI in planning and designing smart solutions for urban and rural environments.

This book is divided into three sections to impart a better understanding of the topics to readers. These sections are: 1) Demystifying smart cities and villages: A traditional perspective, 2) Smart innovations for rural lifestyle management solutions, and 3) Case studies. Through this book, readers will be able to understand various advanced technologies that are vital to the development of smart cities and villages.

The book presents 15 chapters that present effective solutions to urban and rural challenges. Concepts highlighted in chapters include smart farms, indoor object classification systems, smart transportation, blockchains for medical information, humanoid robots for rural education, IoT devices for farming, and much more.

This book is intended for undergraduate and graduate engineering students across all disciplines, security providers in the IT and related fields, and trainees working for infrastructure management companies. Researchers and consultants at all levels working in the areas of artificial intelligence, machine learning, IoT, blockchain, network security, and cloud computing will also find the contents beneficial in planning projects involving smart environments.

Artificial Intelligence, Machine Learning and User Interface Design is a forward-thinking compilation of reviews that explores the intersection of Artificial Intelligence (AI), Machine Learning (ML) and User Interface (UI) design. The book showcases recent advancements, emerging trends and the transformative impact of these technologies on digital experiences and technologies.

The editors have compiled 14 multidisciplinary topics contributed by over 40 experts, covering foundational concepts of AI and ML, and progressing through intricate discussions on recent algorithms and models. Case studies and practical applications illuminate theoretical concepts, providing readers with actionable insights. From neural network architectures to intuitive interface prototypes, the book covers the entire spectrum, ensuring a holistic understanding of the interplay between these domains.

Use cases of AI and ML highlighted in the book include categorization and management of waste, taste perception of tea, bird species identification, content-based image retrieval, natural language processing, code clone detection, knowledge representation, tourism recommendation systems and solid waste management.

Advances in Artificial Intelligence, Machine Learning and User Interface Design aims to inform a diverse readership, including computer science students, AI and ML software engineers, UI/UX designers, researchers, and tech enthusiasts.

An intelligent system is one which exhibits characteristics including, but not limited to, learning, adaptation, and problem-solving. Artificial Neural Network (ANN) Systems are intelligent systems designed on the basis of statistical models of learning that mimic biological systems such as the human central nervous system. Such ANN systems represent the theme of this book. This book also describes concepts related to evolutionary methods, clustering algorithms, and other networks which are complementary to ANN systems.

The book is divided into two parts. The first part explains basic concepts derived from the natural biological neuron and introduces purely scientific frameworks used to develop a viable ANN model. The second part expands over to the design, analysis, performance assessment, and testing of ANN models. Concepts such as Bayesian networks, multi-classifiers, and neuromorphic ANN systems are explained, among others.

Artificial Neural Systems: Principles and Practice takes a developmental perspective on the subject of ANN systems, making it a beneficial resource for students undertaking graduate courses and research projects, and working professionals (engineers, software developers) in the field of intelligent systems design.

This reference presents information about quality benchmarks of Indian higher education institute (HEI) accreditation bodies namely, the National Assessment and Accreditation Council (NAAC) and the National Institute Ranking Framework (NIRF). The objective of the book is to enlighten stakeholders working in Indian HEIs on the recently revised accreditation and ranking processes, which are crucial to the career prospects of students. The contributors of each chapter include experienced NAAC assessors and educationalists. The authors present their own experiences in the light of the accreditation process and suggestions for the improvement of rankings in their institutes. Topics such as the student feedback system, student perception on private and public universities, student mentoring system, usage of ICT methods in teaching learning process, and integration of life skills into curriculum are discussed in this book. The information is presented in a simple, structured manner and is an informative resource for personnel involved in administrative and policy making roles in higher educational settings, with a focus on the Indian higher education system.

Functional foods (foods with known bioactive properties) have shown potential for preventive and therapeutic treatments. However, this potential must be safely determined before they enter the commercial market. At the same time, nutrition research is transforming into a data driven field with reference to the identification and development of functional food products due to the large number of variables affecting food biochemistry in the human body. This volume presents reviews of recent advances in food chemistry, food technology and nutraceutical research (for diet therapy and cosmetics).

Chapters in this volume cover a broad spectrum of topics:

- drug discovery and development in the modern nutraceutical industry,

- recent developments in the extraction, identification and quantification of bioactive peptides in foods,

- concepts of bioavailability, bioaccessibility, bioactivity, bioefficiency and bioconversion of bioactive foods,

- synthetic routes for obtaining bioactive compounds,

- the role of nutrigenomics to identify key cellular functions by specific genetic and epigenetic interactions with a nutrient,

- anti-cancer properties of important bioactive components of medicinal plants,

- the effect of a diet based on different bioactive foods on prevention and treatment of diabetes,

- antioxidant effects on cardiovascular disease,

- beneficial effects of bioactive foods on metabolic syndrome,

- the potential of tauroursodeoxycholic acid on prevention and recovery of neurodegenerative diseases,

- the effects of natural phytochemicals in prostate cancer,

- the effects of methylxanthines (caffeine and others), and culinary methods on physiological and toxicological effects of the bioactive food constituents.

The volume is an ideal reference for pharmacy students, nutritionists, healthcare providers and nutraceutical R&D specialists interested in functional foods.

Augmented intelligence is an alternate approach of artificial intelligence (AI), which emphasizes AI’s assistive role. Augmented intelligence enhances human skills of reasoning in a robotic system or software by simulating expectancy, educational mining, problem solving, recollection, sequencing, and decision-making capabilities. It is based on a combination of techniques such as machine learning, deep learning and cognitive computing.

This book explains artificial intelligence models that support assistive processes in different situations.

The contributors aim to provide information to a diverse audience with groundbreaking developments in mathematical computing.

The book presents 8 chapters on these topics:

- Educational data mining in augmented reality virtual learning environment

- Brain and computer interfaces

- Tree-based tools for chemometric analysis of infrared spectra

- Applications of deep learning in medical engineering

- Bankruptcy prediction model using an enhanced boosting classifier

- Reputation systems for mobile agent security

- The crow search algorithm

- COVID-19 diagnosis and treatment

The contents attempt to integrate various facets of augmented Intelligence, by describing recent research developments and advanced topics of interest to academicians and researchers working on machine learning problems and AI.

Awake thoracic surgery is a new surgical field that is set to expand in the near future. Employing sole epidural or local anaesthesia in fully awake patients renders many thoracic surgical procedures doable with less invasiveness and general anaesthesia related adverse effects can be avoided. This, in turn, facilitates fast track surgery and improves cost-effectiveness of treatment procedures. The book explains issues relevant to awake thoracic surgery including postoperative immunologic and stress-hormone responses, lung volume reduction surgery, pulmonary resections and thymectomy. This Ebook should be useful to readers interested in a comprehensive reference work on this intriguing minimally invasive surgical option.

Bacterial Diseases provides readers an overview of a broad variety of bacterial infections. Chapters cover the description of specific disease and its causative agent, followed by information about symptoms, diagnosis and clinical management. This easy-to-read resource is a suitable introductory textbook for pharmacy, medical, and dental students, as well as M Phil, and Ph.D. candidates for Pharmacology, Botany, Zoology, Microbiology, Pharmacy, Biotechnology and allied health science programs. Readers interested in a simple clinical summary of bacterial diseases can also benefit from the information provided.

Key Features:

- Coverage of a broad spectrum of bacterial infections over 41 topical chapters

- Easy-to-read presentation which provides a basic description of diseases covered to clinical diagnosis and management

- Emphasis on the route of infection

- References for further reading

Balance in Healthcare is an easy to understand guide to maintaining a balanced medium of activities for healthy living. The book points out key aspects of balance in living a healthy life, and gives information on toxic lifestyle elements that can cause imbalance. These aspects include lifestyle, diet, family relationships, spirituality, the immune system, the endocannabinoid system, the antioxidant system and the concept of energy balance in the human body. The contents are expressed in a simple way, while delving into the relevant scientific explanations and also place an emphasis on the positive aspects of relationships and spirituality. Balance in Healthcare therefore, serves as a simple detoxification reference to readers from all walks of life, enabling anyone to understand and relearn the traditional concept of balance from a scientific angle so that they can achieve their highest potential when making choices for their mental and physical well-being.

Basics of Organic Chemistry: A Textbook for Undergraduate Students is an essential guide for students who are learning organic chemistry. The book provides a clear and thorough introduction to fundamental concepts, beginning with the topic of structure and bonding, which lays the foundation by exploring atomic structure, hybridization, and chemical bonds. The second chapter on reaction mechanisms breaks down the processes and factors influencing chemical reactions. The next chapter introduces readers to reactive Intermediates including transient species like carbocations and free radicals, while the final two chapters on Stereochemistry and organic compounds examine the spatial arrangement of atoms and its impact on chemical properties.

Key features

- Clear explanations with detailed illustrations and structured chapters

- Real-world examples to connect theory with practice

- End-of-chapter exercises for self-assessment

- Bibliography for further reading

Designed for undergraduate students of chemistry and allied subjects, this textbook is a valuable resource for advanced studies, in organic chemistry, exam preparation, and laboratory work.

β-Glucan is generally considered to be a very safe immunomodulator. It is a well-known biological response modifier (BRM) that has been used as an adjuvant therapy for cancer since 1980, mostly in Japan. β-Glucan enhances the innate host defense against certain bacteria, yeast, and viral pathogens. I addition, glucans are also considered to be important in prophylaxis against irradiation. Various types of glucans are now routinely added both to human and animal food. At least 26 clinical trials are currently under way in several countries. The authors of this ebook have selected and brought together information on both theoretical and practical aspects of β-glucan use. The book is suitable for readers seeking timely and precise information on β-glucan history and various biological effects including possible use in the treatment of various diseases, without having any preliminary knowledge of natural immunomodulators. The book should not only provide an inspiration for carbohydrate and clinical chemists for further investigations in biomedicine, but it also presents a number of practical applicable results in immunology

Better Life and Business: Cell, Brain, Mind and Sex Universal Laws is an e-book that defines the fascinating new discipline: BRAINLIFEBIZ . BRAINLIFEBIZ combines new discoveries in neurobiology, behavior and medicine with novel concepts related to conscious software programming, automation, system adaptation, module selection , self -organization and automatic discovery. In other words, BRAINLIFEBIZ is a science of the consciousness, bio quantum / random chaos computations, self-organized event trains and processes with several conditions (continuous and discrete; without leadership and central control etc.). The goal of BRAINLIFEBIZ is to create a perfect computer model that simulates animal and human behavior in a computerized experimental setting. This volume presents simulations of the firefly, cricket, katydid, frog, bird and human prefrontal cortex. The book breaks across the lines that separate scientific disciplines. It explains the global nature of the specific intelligent systems outlined above. These intelligent systems features include learning, self- organization, fuzzy logic, high speed signal processing and process control. These features are employed to generate an intelligence map. The map presents figures and equations, curves and data for major ‘Elementary Processes’: aggression, mimicry, chaos , trains, pile up, attractions, courting, mating, emotion, reasoning and consciousness . ‘Elementary Processes’ are then simulated to interact with each other and form millions of complex processes explained by universal laws behind the cell, brain, mind, sex. These laws explain, in a new way, natural selection and reproductive success in the local and global society and business. These laws can be applied in a variety of situations - from everyday stress-free life, to intelligent business decision making, but with a solid biomedical and scientific foundation. The theory behind intelligent systems can be viewed as a complement to the genetic DNA code. The brain generates various brain event trains which allow it to store information in dispersed neural networks (biologically speaking, in 25 billions of neurons some of which with thousands of synapses dispersed over the cortex). The book explains the fast, precise and clear neural diagnostic processas well as the extremely flexible powerful leader mind. Better Life and Business: Cell, Brain, Mind and Sex Universal Laws is, therefore, a valuable reference for researchers to the fascinating world of natural and man -made intelligent systems and their applications in business situations and personal lives..

Beyond Blockchain: Reviewing the Impact and Evolution of Decentralized Networks (Part 2) continues the journey into the rapidly evolving world of blockchain and decentralized technologies. Building on the foundations laid in Part 1, this volume delves deeper into advanced applications such as decentralized finance (DeFi), decentralized identity systems, blockchain governance, and cross-chain interoperability. It also explores the future role of Web3, token economies, and data ownership in reshaping digital ecosystems.

Designed for clarity and accessibility, the book simplifies complex ideas, enabling non-technical readers to grasp the broader implications of decentralization and its growing impact on business, governance, and daily life.

Key Features:

Explains DeFi, DAOs, and decentralized identity with clarity

Explores cross-chain interoperability and next-gen blockchain tools

Highlights blockchain's role in shaping Web3 and digital governance

Examines ethical implications and future regulatory landscapes

Continuation of real-world case studies and thematic insights

Big Data is playing a vital role in HCI projects across a range of industries: healthcare, cybersecurity, forensics, education, business organizations, and scientific research. Big data analytics requires advanced tools and techniques to store, process and analyze the huge volume of data. Working on HCI projects requires specific skill sets to implement IT solutions. Big Data Analytics for Human-Computer Interactions: A New Era of Computation is a comprehensive guide that discusses the evolution of Big Data in Human Computer Interaction from promise to reality. This book provides an introduction to Big Data and HCI, followed by an overview of the state-of-the-art algorithms for processing big data, Subsequent chapters also explain the characteristics, applications, opportunities and challenges of big data systems, by describing theoretical, practical, and simulation concepts of computational intelligence and big data analytics used in designing HIC systems. The book also presents solutions for analyzing complex patterns in user data and improving productivity. Readers will be able to understand the technology that drives big data solutions in HCI projects and understand its capacity in transforming an organization.The book also helps the reader to understand HCI system design and explains how to evaluate an application portfolio that can be used when selecting pilot projects. This book is a resource for researchers, students, and professionals interested in the fields of HCI, artificial intelligence, data analytics, and computer engineering.

Nature has provided opportunities for scientists to observe patterns in biomaterials which can be imitated when designing construction materials. Materials designed with natural elements can be robust and environment friendly at the same time. Advances in our understanding of biology and materials science coupled with the extensive observation of nature have stimulated the search for better accommodation/compression of materials and the higher organization/reduction of mechanical stress in man-made structures.

Bio-Inspired Materials is a collection of topics that explore frontiers in 3 sections of bio-inspired design: (i) bionics design, (ii) bio-inspired construction, and (iii) bio-materials. Chapters in each section address the most recent advances in our knowledge about the desired and expected relationship between humans and nature and its use in bio-inspired buildings. Readers will also be introduced to new concepts relevant to bionics, biomimicry, and biomimetics.

Section (i) presents research concepts based on information gained from the direct observation of nature and its applications for human living.

Section (ii) is devoted to ‘artificial construction’ of the Earth. This section addresses issues on geopolymers, materials that resemble the structure of soils and natural rocks; procedures that reduce damage caused by earthquakes in natural construction, the development of products from vegetable resins and construction principles using bamboo.

The last section takes a look into the future towards the improvement of human living conditions.

Bio-Inspired Materials offers readers - having a background in architecture, civil engineering and systems biology - a new perspective about sustainable building which is a key part of addressing the environmental concerns of current times.

Bioactive Compounds Targeting Neurodegenerative Diseases explores the therapeutic potential of natural bioactive compounds in preventing and managing neurodegenerative disorders such as Alzheimer's, Parkinson's, and Huntington's disease. The book integrates insights from neuroscience, pharmacognosy, and nanotechnology to highlight innovative strategies for drug delivery and treatment. Chapters cover plant-based bioactives, advanced nano-carriers, intranasal administration, and blood-brain barrier targeting. It also discusses clinical approaches, current treatment challenges, and intellectual property considerations.

Key Features:

- Comprehensive overview of natural bioactive compounds in neurodegenerative therapy.

- Coverage of phytochemicals, nano-delivery systems, and intranasal administration.

- Insights into the blood-brain barrier and clinical management strategies.

- Discussion on current therapies and intellectual property issues.

Bioactive Phytochemicals from Himalayas: A Phytotherapeutic Approach covers herbal medicines from the Himalayan mountains. Chapters in this book detail molecular mechanisms and experimental tools and techniques for research on plants in this region. Phytochemical experts guide the readers through the role of Himalayan plants in therapy for metabolic diseases like cancer and diabetes, hepatic diseases, inflammatory diseases, and neurodegenerative diseases. Some chapters focus on diseases and how various plants from Himalayan origin are beneficial in these diseases.

This compilation,with professional contributors, aims to inform a wide scientific community from various research fields about basic research on medicinal plants with a focus on Himalayan herbs. The book also serves as a handbook for pharmacologists working on the broad therapeutic aspects of these plants.

This book explores cutting-edge biocarbon polymer composites. The book brings together nine edited chapters that explore the development, properties, and applications of these eco-friendly materials, highlighting their potential to transform industries and reduce the environmental impact of traditional polymers. Spanning a range of critical topics, this book begins with an introduction to biocarbon and polymer materials, providing a solid foundation. It then progresses into the latest research on biocarbon sources, processing techniques, and characterization methods. Subsequent chapters cover the mechanical, thermal, and electrical properties of biocarbon polymer composites, along with their applications in diverse industries such as automotive, construction, and packaging. Contributors highlight real-world case studies and examples to showcase the practical relevance of these materials.

Readers will gain a comprehensive understanding of the science and technology behind biocarbon polymer composites, enabling them to make informed decisions in materials selection and development. In an era of increasing environmental consciousness, this book emphasizes the eco-friendly nature of biocarbon composites, offering sustainable alternatives to traditional plastics. Additionally, this book bridges the information gaps between different disciplines and it is intended for a wide range of readers, from materials scientists and engineers to environmentalists and industry policymakers.

Bioceramics: Status in Tissue Engineering and Regenerative Medicine (Part 2) presents recent advancements in biocompatible ceramics and bioactive glasses, emphasizing their expanding applications in hard and soft tissue engineering. This book explores innovative manufacturing techniques like 3D printing and additive manufacturing and examines the therapeutic potential of bioceramics in areas such as bone regeneration, microbial infection management, wound healing, and cancer treatment. It also discusses current challenges, clinical applications, and future research directions. This book is a valuable resource for those developing biocompatible materials for medical applications.

Key Features:

- Comprehensive overview of bioceramic and bioactive glass applications in tissue engineering.

- In-depth analysis of manufacturing techniques, including 3D printing and additive manufacturing.

- Insights into clinical challenges, preclinical assessments, and future perspectives in regenerative medicine.

Aluminium is a chemical element present in earth’s crust and it is a known environmental toxin which has been found to be associated with various neurological disorders. Aluminium has been found to be a very strong risk factor for the development of Alzheimer’s disease.

Biochemical Mechanisms of Aluminium Induced Neurological Disorders explains the association of aluminium with neurological disorders. The book introduces the reader to sources of aluminium exposure, followed by an explanation of pharmacokinetics of aluminium and the different biochemical pathways that cause neurological effects. Chapters cover the typical mechanisms associated with aluminium neurotoxicity such as synaptic impairment as well as recent topics of interest such as the role of aluminum in impairing blood-brain barrier functions. Separate chapters which cover clinical evidence of aluminium toxicity and its management are also included in the book.

Biochemical Mechanisms of Aluminium Induced Neurological Disorders is a concise, yet informative reference on the subject of aluminium neurotoxicity for all readers, whether they are students of biochemistry, pharmacology and toxicology, clinical neurologists, environmentalists interested in metal pollution or general readers who want to learn about the toxic effects of aluminium in humans.

This book is a concise textbook of iatrogenic pathology. Chapters cover iatrogenesis relevant to a broad range of medical subspecialties (cardiology, gastroenterology, gynecology, neurology, endocrinology and much more). The book presents an introduction to iatrogenesis which is followed by chapter-wise descriptions of iatrogenic lesions (lesions due to adverse drug reactions, lesions occurring during diagnosis and consequences of various therapeutic interventions) of the organs and systems of the body.

This textbook is a handy resource on iatrogenic pathology for medical students and working professionals (clinical and nursing staff) involved in a range of medical subspecialties

Naturally-derived biomaterials invite immense interest from diverse segments of science and engineering. Recent decades have witnessed a leap in knowledge and efforts in ongoing research with biomaterials as synthons, yet biomaterial research never fails to create surprises. This book summarizes modern knowledge of bioderived materials for beginners in research and advanced readers in materials science.

The book lays the foundations of understanding the design and development of mimetic peptides and enzyme mimetic bioinorganic catalysts, including the toolsets used in the process. Next, the book demonstrates different approaches for obtaining task-specific designer hydrogels. Additional topics covered in the book are tissue engineering and regenerative medicine. From this point, the book presents information on complex biomaterials systems: bacterial cellulose, cell membrane architecture for nanocomposite material design, and whole cellular microorganisms. Chapters provide applied knowledge with information on the strategies used to design novel biomaterials for applications such as drug delivery, therapy and controlled chemical synthesis.

In summary, this book brings together a wealth of information on bioderived materials with versatile applications, derived from different sources, such as plant derivatives and microorganisms (in part or whole as synthons), benefitting readers from multidisciplinary backgrounds.

This brief book is dedicated to the quantitative analyses and systematic discussion of spatial biodiversity and biogeographic patterns in the Asia‐pacific region comprised of China, India and adjacent countries. The book is split into two sections. The first section presents readers with detailed statistical methods to conduct spatial macro‐biodiversity and biogeography analyses. Step-by-step instructions on how to perform these statistical methods by using the statistical program R are also provided. In the second part, different quantitative case studies are presented covering several topics, including phylogenetics, spatial statistics, multivariate statistics and ecological genomics. Each case study concludes with a detailed interpretation of the quantitative results and how these results are relevant to local and regional ecological processes. This reference is suitable for academics interested in biostatistics biodiversity and ecological studies specific to the Asia Pacific region and China.

Bioencapsulation (or microencapsulation) of cells and their implantation into a body of immunoprotected cells allows researchers to revive a missing or defective function in the cells. Microencapsulated cells have reached the clinic where they have been shown to be safe and efficacious in numerous clinical trials. Cell types that have been encapsulated for therapeutic purposes include hybridomas, islet cells, "platform" cell lines e.g. HEK293 and CHO cells as well as an increasing focus on the encapsulation of stem cells. This e-book explains the different methods used for achieving cell bioencapsulation based on different polymers e.g. alginate, cellulose sulphate and agarose. Other chapters in this book subsequently describe the use of cell encapsulation in cancer therapy to improve on existing chemotherapies by reducing doses and thus side effects while increasing efficacy for long term in vivo production of (i) tumoricidal or virus neutralising antibodies, (ii) insulin to achieve a self regulating treatment for diabetes and (iii) neuron nurturing factors to treat CNS diseases such as epilepsy, disorders like Parkinson's disease, Alzheimer, Amyotrophic lateral sclerosis, Huntington's disease and pathologies caused by trauma and/or ischemic processes. The book also includes a chapter reviewing the genetic engineering of cells to allow controlled production of biotherapeutics from encapsulated cells.

This is a unique and timely book which brings together contributions from some of the leading researchers in the field of cell encapsulation. Interested readers are provided an overview of the exciting developments and clinical experiences of researchers with cell bioencapsulation.

Both Asia and Africa are home to many plants that can be used for the treatment of many diseases and their medicinal properties are gaining interest in western societies. Medicinal plants from Asia and Africa are used for their healing abilities and also have a symbolic meaning in communities.

The importance of traditional autochthonous plant remedies plays a crucial role in the health of millions of people of these two continents. Even today, traditional medicine represents the dominant medical system for millions of people showing a significant impact on health care practices. Therefore, traditional operators still represent a vital part of regional healthcare systems. For this reason, pharmaceutical industries consider traditional medicine as a source for the identification of bioactive compounds that can be used in the preparation of synthetic drugs.

Biologically Active Natural Products from Asia and Africa: A Selection of Topics guides the reader to information about new natural products from these regions and the different ways to use them to treat or alleviate many of the most common diseases. The volume presents nine topics covering a number of facets of natural product medicine including:

- pharmaceutical analysis of anti-diabetic herbal medicines from Bangladesh and local retailers

- caffeine intake and the risk of female infertility

- pharmaceutical analysis of Urena sinuata (bur mallow)

- anti-CHIKV activities of diterpenes and their derivatives

- anti-inflammatory nanogel for the treatment of psoriasis

- antlithiatic properties of Moroccan medicinal plants

- ethnobotanic, phytochemical and biological activities of Aristolochia longa L. (pipevine)

- wound healing potential of combined extracts of stem bark and leaves of sphenocentrum jollyanum (an African shrub)

This is a handy reference for specialists and R&D experts in pharmaceutical chemistry who wish to be informed about current knowledge on developing natural remedies in Asia and Africa

Bioluminescence, the cold living light or the cold fire of the sea is extremely common in all oceans at all depths. However, this phenomenon is nearly absent in freshwater, with the exception of a freshwater limpet. More than 75% of deep-sea creatures have been reported to produce their own light. The luminescent marine plankton such as dinoflagellate, radiolarians, jellyfish, comb jellies, annelids, copepods, ostracods, mysids, amphipods, euphausiids, and tunicates form an important component in the marine food chain. Research on luminescent marine plankton is gaining momentum owing to its importance in life science research and medicine. The glowing Green Fluorescent Protein (GFP) extracted from the North Pacific jellyfish, Aqueorea victoria (for which the Japanese biologist, Osamu Shimonmura won the Nobel Prize in Chemistry in 2008) has helped shed light on key processes such as the spread of cancer, the development of brain cells, the growth of bacteria, damage to cells by Alzheimer's disease, and the development of insulin-producing cells in the pancreas. Therefore, it is difficult to underscore the importance of bioluminescence and the organisms associated with this phenomenon.

Bioluminescent Marine Plankton is a unique reference that attempts to provide answers to questions about bioluminescence. The first of its kind, this book attempts to answer questions on the subject with a focus on planktonic organisms. 12 chapters provide information about the chemistry of bioluminescence, types of bioluminescent displays, distribution of bioluminescence among marine plankton, ecological functions and utility of planktonic bioluminescence. Chapters are dedicated to the biology and ecology of specific groups of plankton that span about 200 luminescent marine species.

The detailed book is an essential compendium on marine plankton for a broad range of readers who want to learn about bioluminescent plankton. A list of detailed references is also provided for the benefit of teachers, students, researchers and enthusiasts interested in marine biology, aquaculture, and environmental sciences.

This reference is a guide to biomaterial fabrication techniques. The book comprises ten chapters introducing the reader to a range of biomaterial synthesis while highlighting biomedical applications. Each chapter presents a review of the topic followed by updated information about relevant core and applied concepts in an easy to understand format. The first two chapters present vital information about biomaterial components, such as polymer nanocomposites and scaffolds, and the strategies used for their fabrication. The proceeding chapters explain the principles of the most widely used fabrication techniques, and their application in detail. These include freeze drying, electrospinning, 3D printing, multiphoton lithography, particulate leaching, supramolecular self assembly, solvent casting and melt molding. The book is an essential primer on biomaterial synthesis for students and early career researchers in the field of biomedical engineering, applied chemistry and tissue engineering.

Biomedical Applications of Perovskites: The Era of Bio-Piezoelectric Systems focuses on recent developments in the area of piezoelectric systems and their biomedical applications. A compilation of 19 edited chapters covers different piezoelectric materials, device designs, and their use cases. Readers will be familiarized with the many perovskite materials being used in research and development as well as the role they play in designing novel medical devices and biomaterials.

Key Features

- systematically explains the piezoelectric perovskite materials starting from their introduction, their structure and synthesis techniques

- explains the key materials used in devices such as pacemakers and nanogenerators

- highlights a range of applications including bone regeneration and growth, bone replacement, tissue engineering, dental science, neurotrauma and neurodegenerative disease treatment and bionic prosthesis

- discusses future challenges and the roadmap for piezoelectric perovskite materials

- Presents scientific references for advanced reading

The biophysics of diving and decompression in the human body are complex. The average individual experiences atmospheric pressure swings of 3% at sea level and over 20% at altitudes greater than a mile. Divers and their equipment can experience compressions and decompressions in orders of greater magnitude than pressures outside water, all within considerably shorter time spans. The understanding of the mechanics behind diving is based on absolute pressure and pressure changes. While these mechanics are readily quantified in physics, chemistry, and engineering applications, the physiological and medical aspects of pressure changes in living systems need to be understood clearly to assess the safety of routine divers.

This monograph is a compilation of a body of knowledge on biophysics, gas transport, bubble studies and physiological models used for diving and hyperbaric applications. Information in the monograph is divided into three parts that cover biophysics and models, data correlation and validation approaches and practical applications, respectively. The book is a useful resource for researchers and maritime professionals who wish to understand the biophysics behind underwater diving and decompression for the purpose of maritime operations as well as diving simulation applications.

Increased industrial and agricultural activity has led to the contamination of the earth's soil and groundwater resources with hazardous chemicals. The presence of heavy metals, dyes, fluorides, dissolved solids, and many other pollutants used in industry and agriculture are responsible for hazardous levels of water pollution. The removal of these pollutants in water resources is challenging. Bioremediation is a new technique that employs living organisms, usually bacteria and fungi, to remove pollutants from soil and water, preferably in situ. This approach is more cost-effective than traditional techniques, such as incineration of soils and carbon filtration of water. It requires understanding how organisms consume and transform polluting chemicals, survive in polluted environments, and how they should be employed in the field.

Bioremediation for Environmental Pollutants discusses the latest research in green chemistry and practices and principles involved in quality improvement of water by remediation. It covers different aspects of environmental problems and their remedies with up-to-date developments in the field of bioremediation of industrial/environmental pollutants. Volume 1 focuses on the bioremediation of heavy metals, pesticides, textile dyes removal, petroleum hydrocarbon, microplastics and plastics.

Waste management is one of the major challenges for environmental and public health organizations for maintaining safety standards in any area. Population growth and urbanization increase the difficulty in maintaining a sustainable waste management system. Bioremediation refers to the use of living organisms in processes designed to remove toxic chemicals present in waste material. Bioremediation represents a sustainable way to remove a range of environmental pollutants.

Bioremediation: Challenges and Advancements covers the subject of bioremediation in eight chapters that focus on a broad range of waste sources, their adverse impacts on the ecosystem, and the advanced strategies for their remediation. Each chapter also highlights the problems encountered in bioremediation processes.

Key features:

- Comprehensive coverage of bioremediation in 8 reader-friendly chapters

- Highlights methods and challenges of bioremediation in one volume.

- Introduces the reader to bioremediation

- Explains recent biotechnological methods for removing heavy metals and xenobiotic compounds

- Describes strategies including physical, chemical, and biological methods to mitigate radioactive waste from contaminated sites and water bodies

- Details the use of microbial-aided remediation techniques for the management of biomedical and electronic wastes, and its impact on the ecosystem

- Describes bioremediation technologies for decontamination of solid waste pollutants

- Showcases the application of Omics approaches such as genomics, transcriptomics, proteomics, and metabolomics to improve bioremediation processes.

- Covers bioremediation of agro-wastes

- Includes detailed references

This book is an informative reference for scholars (researchers, undergraduate and graduate students of environmental sciences, microbiology and biotechnology) professionals (environmental engineers) and researchers, giving each a good understanding of the significance of bioremediation in solid waste management and the restoration of contaminated sites.

Increasing public health concern about healthy lifestyles has sparked a greater demand among consumers for healthy foods. Natural ingredients and environmental friendly food production and processing chains are more aligned to meeting the demand for healthy food. There is a wide array of food additives and chemicals that have nutritional value. The biotechnological food production processes, therefore, vary for different types of food chemicals and ingredients accordingly.

Biotechnological Production of Natural Ingredients for Food Industry explains the main aspects of the production of food ingredients from biotechnological sources. The book features 12 chapters which cover the processes for producing and adding a broad variety of food additives and natural products, such as sweeteners, amino acids, nucleotides, organic acids, vitamins, nutraceuticals, aromatic (pleasant smelling) compounds, colorants, edible oils, hydrocolloids, antimicrobial compounds, biosurfactants and food enzymes.

Biotechnological Production of Natural Ingredients for Food Industry is a definitive reference for students, scientists, researchers and professionals seeking to understand the biotechnology of food additives and functional food products, particularly those involved in courses or activities in the fields of food science and technology, food chemistry, food biotechnology, food engineering, bioprocess engineering, biotechnology, applied microbiology and nutrition.

Biotechnology and Drug Development for Targeting Human Diseases is an insightful compendium on drug development technologies for professionals and students in biotechnology and pharmacology. This book meticulously explores the intersection of biotechnology with drug development, emphasizing its crucial role in creating new therapies for human disease.

Central to the book is the innovative use of biotechnology in understanding and treating diseases. It begins with an exploration of multi-omics profiles, shedding light on disease mechanisms and drug development. Subsequent chapters explain in silico methods for drug design, the role of natural products in antimicrobial applications and wound healing, and the use of viruses as carriers in biotechnology.

Key features of this reference include a blend of theoretical knowledge and practical insights, detailed analyses of molecular docking in drug discovery, the repurposing of drugs for various diseases, and the emerging field of omics technologies in drug interaction studies. Each chapter is comprehensive, offering current information backed by extensive references, making the book both a foundational and advanced resource.

This reference presents information about different facets of IoT and blockchain systems that have been recently proposed for practical situations. Chapters provide knowledge about how these technologies are applied in functions related to trust management, identity management, security threats, access control and privacy.

Key Features:

- Introduces the reader to fundamental concepts of IoT and blockchain technology

- reports advances in the field of IoT, ubiquitous computing and blockchain computing

- includes the applications of different frameworks

- explains the role of blockchains in improving IT security

- provides examples of smart grids, data transmission models, digital business platforms, agronomics and big data solutions

- Includes references for further reading

Blockchain Applications for Secure IoT Frameworks: Technologies Shaping the Future is a handy reference for information technology professionals and students who want updated information about applications of IoT and blockchains in secure operational and business processes.

This volume reviews cutting-edge innovations in blockchain technology that are propelling the healthcare industry into a new era of efficiency and security. It brings 14 reviews contributed by experts in blockchain and Web3 technologies into a single volume. Each contribution includes a summary for easy understanding and scientific references for advanced readers.

Key Themes:

Empowering Decentralized Healthcare: Learn about the future of decentralized healthcare, powered by blockchain, ensuring a seamless and patient-centric experience.

Clinical Trials: Discover how blockchain is reshaping clinical trials, offering a glimpse into a future of optimized medical research.

Data Security: Uncover the strategic use of blockchain in securing vital clinical trials data, ensuring confidentiality and integrity at every step.

Blockchain-based Healthcare delivery: Delve into a comprehensive review of blockchain technology in the health sector, revealing its potential to transform healthcare systems with

Predict, Prevent, and Protect: Understand how blockchain technology serves as a predictive tool, aiding in the prevention and control of the spread of COVID-19.

This volume is a must-read for healthcare practitioners and administrators seeking to harness the power of blockchain in medicine and healthcare. It also provides information for researchers and business professionals who want to understand the innovative role of blockchain technology in the healthcare sector.

Blockchain-Enabled Internet of Things Applications in Healthcare: Current Practices and Future Directions examines cutting-edge applications, from blockchain-powered IoT innovations in healthcare systems to intelligent health profile management, remote patient monitoring, and healthcare credential verification. Additionally, the book extends its insights into blockchain-enabled IoT applications in smart agriculture, highlighting AI-driven technologies for health management and sustainable practices.

With expert analyses, case studies, and practical guidance, this book offers readers a roadmap for implementing these technologies to improve efficiency, security, and data management in healthcare. It is an invaluable resource for industry professionals, researchers, and students interested in the future of healthcare technology.

Key Features:

- Exploration of blockchain and IoT applications in healthcare and agriculture

- In-depth case studies and expert analyses

- Practical insights into technology challenges and benefits

Body contouring is a rapidly growing field within plastic surgery. Safe and effective techniques have been developed in recent times with increased patient satisfaction indicated by visual analogue scores.

This book brings together contributions from leading experts in bariatric surgery from all across the globe. The body contouring techniques and procedures described in the book have been developed specifically to treat massive weight loss patients in contrast to traditional methods that are normally unsuitable for such patients. These procedures focus on maximizing the removal of excess and unwanted skin whilst preserving volume and restoring contour. The key issue of patient safety is also addressed in the book.

Body Contouring Following Bariatric Surgery and Massive Weight Loss should be a useful resource for surgeons and clinicians interested in massive weight loss surgery and satisfactory visual analogue scores.

This reference book explains the fundamentals of Bose Einstein Condensation (BEC) in excitons and polaritons. It presents five chapters exploring fundamental concepts and recent developments on the subject. Starting with a historical overview of BEC, the book progresses into the origins and behaviors of excitons and polaritons. Chapters also cover the unique thermalization and relaxation kinetics of excitons, and the distinctive features of polaritons, such as lasing, superfluidity, and quantized vortices.

The chapters dedicated to BEC in excitons and polaritons detail experimental techniques, theoretical modeling, recent advancements, and practical applications in a simplified way for beginners. This book serves as a resource for researchers, physicists, and students interested in the phenomena of BEC, providing insights into both the theoretical foundations and the practical implications of excitons and polaritons.

The mathematical modelling of free and moving boundary problems are an important topic in engineering, industry, technology and theoretical sciences. These models allow us to make calculations involved in phase change transitions of materials due to heat transfer.

Boundary layer applications are widespread in research and industry. Boundary Element Methods for Heat Transfer with Phase Change Problems: Theory and Application equips the reader with information about heat transfer problems occurring during phase changes. The book covers several boundary element methods, including methods for phase changes, fixed and moving domains and new approaches. The contents are rounded off with chapters on numerical results and industrial applications.

Key features:

- Simple, didactic presentation of boundary layer problems for heat transfer problems

- Covers a wide range of boundary element methods

- Includes methods for fixed and moving domains

- Explains industrial applications of the methods

- Includes solutions to numerical problems

The book serves as a textbook for students of advanced mathematics and engineering. It is also a handbook for researchers working on numerical analysis, who require a focused volume on boundary element methods for heat transfer applications.

Brain Tumor Targeting Drug Delivery Systems: Advanced Nanoscience for Theranostics Applications is a comprehensive reference focused on the latest advancements in nanotechnology for brain tumor therapy. With practical insights and cutting-edge research, this book equips readers with the knowledge to develop innovative drug delivery systems for effective brain tumor diagnosis and treatment. Structured into insightful chapters, this book covers the anatomy, physiology, and pathophysiology of the brain, addressing barriers to targeted drug delivery strategies. Chapters explore theranostics-based delivery systems, including polymeric nanoparticles, liposomes, dendrimers, nanoemulsions, micelles, and inorganic nanoparticles, for precise brain tumor diagnosis and treatment. This informative resource is designed for students and research scholars in pharmacology, pharmaceutical industry scientists, professors, and clinical medicine researchers. With comprehensive chapters and references for further reading, this book facilitates easy understanding of the intricate nanomedical technology, empowering researchers to make significant strides in the field of brain tumor therapy. Key Features: - Structured chapters for easy understanding of nanotechnology concepts - In-depth coverage of theranostics-based delivery systems for brain tumor diagnosis and treatment - References for further reading and exploring new advances in drug delivery systems

Breast cancer is one of the most common cancer types worldwide, and is a leading cause of cancer related deaths in women. In this book, medical experts review our current understanding of the molecular biology and characteristics of breast cancer. The topics covered in this book provide comprehensive knowledge of mechanisms underlying breast carcinogenesis, and are intended for a wide audience including scientists, teachers, and students.

11 chapters present information about several topics on breast cancer, including the role of cell growth and proliferation pathways, androgen and cytokine signaling, germline mutations in breast cancer susceptibility genes, and molecular factors causing invasive and metastatic breast cancer. In addition, the editors discuss the recent advancements in multi-omics data analysis based on inter-and intra-tumor molecular profiles.

The reference highlights how the knowledge and understanding of the biological behavior of breast neoplasms have facilitated ongoing investigations into dietary polyphenolic compounds with antioxidant properties, making them function as cancer chemopreventive agents. Along with this, the current development of treatment strategies such as targeted molecular therapy, and radiation therapy is brought to the fore to update readers.