Bentham Science Publishers

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field.

Contents of this volume include these 7 reviews:

- Recent advances in copper-catalyzed heterocyclic syntheses

- Application of modern green chemistry methods in the synthesis of quinolines, quinazolines and quinazolinones - Electroluminescence polymers-a review on synthesis by organic compounds - Multicomponent approach for the synthesis of xanthenes - From atoms to macromolecules: 100 years of polymer research - An overview of oxidizing and reducing agents in total synthesis - Amino acid-derived ionic liquids: novel biodegradable catalytic systems for green synthesis of heterocycles

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field.

Volume 18 presents 7 reviews focused on ionic materials, nanoparticles and nitrogen containing heterocycles in organic synthesis.

- Recent synthetic and biological advances in anti-cancer ferrocene-analogues and hybrids

- Synthesis of fused nitrogenated heterocycles: intramolecular povarov reaction

- Use of barbituric acid as a precursor for the synthesis of bioactive compound

- Ionic liquids as solvents and/or catalysts for organic synthesis

- Zinc oxide nanomaterials for biomedical applications

- Superhydrophobic polymeric nanocomposites coatings for effective corrosion protection

- Morphologies and properties of virgin and waste PP nanocomposites

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. It presents comprehensive articles written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations. Contributions are written by eminent scientists and each volume is edited by an authority in the field. Advances in Organic Synthesis is essential for all organic chemists in the academia and industry who wish to keep abreast of rapid and important developments in the field.

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. It presents comprehensive articles written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations. Contributions are written by eminent scientists and each volume is edited by an authority in the field. Advances in Organic Synthesis is essential for all organic chemists in the academia and industry who wish to keep abreast of rapid and important developments in the field.

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. It presents comprehensive articles written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations. Contributions are written by eminent scientists and each volume is edited by an authority in the field. Advances in Organic Synthesis is essential for all organic chemists in the academia and industry who wish to keep abreast of rapid and important developments in the field.

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field.

This volume presents the following reviews:

Asymmetric hydrogenation of tetrasubstituted olefins

Recent advances in catalytic organic synthesis applications of covalently supported ionic liquids

Recent developments in intramolecular cyclization reactions via carbon-heteroatom (c-x) bond formation

• Efficient synthetic protocol and mechanistic study of quinazoline analogues and their biological importance

Synthesis of N,O,S-heterocycles by one-pot reactions of epoxides, aziridines and oxaziridines

There is considerable diversity in polymers extracted from natural sources and much work has been done to classify them according to their physical and chemical properties.

In the second part of this book set, readers will find general information about the physicochemical properties of several naturally occurring polysaccharides followed by a section dedicated to their application in different fields of research and medicine. Key topics in this part include:

• chitosan (properties modifications and applications)

• microbial biopolymers

• biopolymers present in Brazilian seeds

• protein-plastic foams

• biopolymer microencapsulation in the food industry

• biomedical gels

• collagen biomaterials

• biopolymer electrospinning

This reference is intended for students of applied chemistry and biochemistry who require information about the properties and applications of polysaccharides (such as chitosan) and other protein-based biopolymers.

Time series analysis is applicable in a variety of disciplines, such as business administration, economics, public finance, engineering, statistics, econometrics, mathematics and actuarial sciences. Forecasting the future assists in critical organizational planning activities. Time series analysis is employed by many different organizations such as hospitals, universities, commercial enterprises or government organizations in order to forecast future scenarios. Therefore, many time series forecasting methods have been proposed and improved in statistical literature. Linear models such as Box-Jenkins methods were earlier used in many situations. Then, to overcome the restrictions of these linear models and to account for certain nonlinear patterns observed in real problems, some nonlinear models are also presented in literature. However, since these nonlinear models were developed for specific nonlinear patterns, they are not suitable for modeling other types of nonlinearity in time series. In recent years, efficient and advanced techniques such as artificial neural networks, fuzzy time series and some hybrid models have been used to forecast any kind of real life time series analyses. Both theoretical and empirical findings in academic literature show that these approaches give comparatively reliable forecasts than those obtained from conventional forecasting methods. In addition, conventional models require some assumptions such as linearity and normal distribution or cannot be utilized efficiently for some real time series such as temperature and share prices of stockholders since these kind of series contain some uncertainty. However, when advanced methods such as neural networks and fuzzy time series are used to forecast time series, there is no need to satisfy any assumption and the time series containing uncertainty can be forecasted efficiently.

This e-book contains recent effective applications and descriptions of these advanced forecasting methods. Readers will learn how these methods work and how these approaches can be used to forecast real life time series. In addition, the hybrid forecasting model approach, which combines different methods to obtain better forecast results, is also explained. Readers can also find the applications of hybrid forecasting models in this e-book. This e-book also enables skilled statisticians to create a new hybrid forecasting model suitable for their own objectives. Data presented in this e-book is problem based and is taken from real life situations. This e-book is a valuable resource for students, statisticians and working professionals interested in advanced time series analysis.

Determining the presence of different types of toxic compounds (or xenobiotics) in food requires precise analytical methodologies. Examples of these techniques include separation techniques coupled to mass spectrometry, Variations in methods used depend on the physicochemical properties of each xenobiotic being tested for.

Advances in the Determination of Xenobiotics in Foods explains recent developments in the field of xenobiotic determination in food. Readers are introduced to xenobiotic testing techniques through extensive reviews. Chapters also cover details about contaminants coming from food contact materials (such as plasticizers, food additives, polymer monomers/oligomers and non-intentionally added substances), substances used for food processing and sensing (nanoparticles), and residues of pesticides (that can also be present in the final food product). The book also includes information about specific xenobiotics that, due to their global distribution in the environment, are also likely to enter the food chain. Some of them are regulated (persistent organic pollutants and heavy metals) but there are many other types of contaminants (halogenated flame-retardants, perfluorinated compounds and micro- and nanoplastics) that must also be controlled. In addition, some xenobiotics could be present in the final food consumed because of food treatments (acrylamide, furan, heterocyclic aromatic amines, and glycidol esters). Finally, the concluding chapters of the book are devoted to the presence of natural contaminants such as mycotoxins and biogenic amines.

The combination of extensive information of analytical techniques for xenobiotics along with a categorical treatment of food contaminants makes this volume a handy reference for food science and technology students and technicians involved in food safety and processing management roles.

SERIES INTRODUCTION:

This book series presents reviews, and reference monographs on all aspects of food science and technology. The series is essential reading for food chemists and technician in both professional and academic settings.

Advances in the Medicinal Chemistry of Neglected Tropical Disease and Related Infectious Diseases offers an in-depth overview of recent progress in drug discovery targeting some of the world's most persistent and under-researched diseases. With a focus on medicinal chemistry and target-based drug design, this book explores critical pharmacological targets and innovative compounds aimed at combating neglected tropical diseases (NTDs) and related infections.Spread across ten chapters, the book examines the current state and future directions of therapeutic research for diseases such as leishmaniasis, Chagas disease, sleeping sickness, malaria, schistosomiasis, dengue, Zika virus, tuberculosis, and fascioliasis. Each chapter provides details about disease-specific targets, structural activity relationships (SAR), and developments in promising lead compounds over the past decade.

Key features:

Focuses on pharmacological targets and medicinal chemistry strategies

Covers both parasitic and viral diseases with global health impact

Underlines emerging therapeutic approaches and SAR-guided design

Explains compound screening, optimization, and preclinical research

African Meteorites is a comprehensive exploration of meteorite falls and finds across the arid and hot regions of the African continent, offering profound insights into a significant collection of meteorites, second only to Antarctica. The book is divided into seven chapters, covering the origin and formation of meteorites, statistical analyses of meteorite falls in African countries, classes and mass distribution of meteorite finds, allocation and renaming of North West African (NWA) meteorites, exceptional and rare meteorite falls and finds in Eastern Morocco Sahara, protocols for recognizing, recovering, and preserving meteorites in Sahara, and a review of confirmed and proposed meteorite falls, finds, and impact structures in Egypt, Sudan, and Libya. With detailed and updated references complementing the simple presentation, this book is an invaluable resource for meteoriticists, hunters, museums, astronomers, students, and geology and astronomy enthusiasts, on the origin, characteristics, and collection of meteorites discovered in Africa. Key Themes: Meteorite origin, formation, and classification Meteorite falls and finds in Africa Unique features of North West Africa (NWA) meteorites Rare and exceptional meteorite falls and finds in Eastern Morocco Sahara Protocols for recognizing and preserving meteorites in the Sahara Meteorite falls, finds, and impact structures in Egypt, Sudan, and Libya

Banana farming is the basis for commercial fruit trading. Every banana plant generates waste biomass nearly ten times the quantity of its fruits. Disposal of waste biomass is a burden for the farmers. Economical use of the waste biomass can bring financial benefit to banana farmers. Use of organic potash in lieu of inorganic potash affords higher yield and also helps to preserve the ecosphere of soil for subsequent crops. Agricultural Benefits of Postharvest Banana Plants details the use of postharvest banana plants for agriculture and trade. Eleven chapters explain both traditional and modern uses of banana plants. The reader is informed how bio-waste from postharvest banana plants (including their stems) can be used as organic potash to replace inorganic potash (muriate of potash) in fertilizer. Experimental uses of banana plant pseudo-stem juice for growing different crops along with chemical analysis of the pseudo-stems are explained in separate chapters. Isolations of potassium chloride and potassium carbonate have also been discussed in the latter part of the book.

This book is an ideal handbook for professionals and trainees interested in utilizing postharvest banana plants for sustainable agriculture and trade. The information is also useful for students and teachers involved in agricultural biotechnology and traditional agriculture courses.

Intensive use of fossil-based energy sources causes significant environmental problems on a global scale. Researchers have been working for several decades to find alternative energy solutions to fossil fuels. Algae are a renewable energy source, with high potential for increasing scarce resources and reducing environmental problems caused by fossil fuel use.

Algal Biotechnology for Fuel Applications gives the reader a comprehensive picture of the industrial use of algae for generating power. This book informs readers about the existence of alternative species to the currently used algae species for biofuel production, while also explaining the methods and current concepts in sustainable biofuel production.

Key Features

- Fifteen chapters covering topics on commercial algae species and algal biofuel production.

- Covers anaerobic biotechnology and basic biofuel production from thermal liquefaction

- Covers biodiesel production and algal biofuel characterization

- Introduces the reader to applied microbial fuel cell technology and algae cultivation methods

- Provides concepts about ecological engineering

- Covers microalgae culture and biofuel production techniques

- Explains the importance of catalysts

- Explains the economic evaluation of algae fuel production technology

This reference is essential reading for students and academics involved in environmental science, biotechnology, chemical engineering and sustainability education programs. It also serves as a reference for general readers who want to understand the ins and outs of algal biofuel technology.

Medicinal chemists around the world have been inspired by nature and have successfully extracted chemicals from plants. Research on enzymatic modifications of naturally occurring compounds has played a critical role in the search for biologically active molecules to treat diseases.

This book set explores compounds of interest to researchers and clinicians. It presents a comprehensive analysis about the medicinal chemistry (drug design, structure-activity relationships, permeability data, cytotoxicity, appropriate statistical procedures, molecular modelling studies) of different compounds. Each chapter brings contributions from known scientists explaining experimental results which can be translated into clinical practice.

Volume 3 presents (1) a brief overview of botanical and pharmacological properties of alkaloids, (2) a summary of the synthesis of natural morphinans and related alkaloids, (3) caffeine-based compounds for the treatment of neurodegenerative disorders, (4) piperine derivatives, (5) noscapine-based anti-cancer agents, (6) biogenic amines and amino acid derivatives as carbonic anhydrase modulators and (7) antimalarial compounds on quinoline scaffolds.

The objective of this book is to fulfil gaps in current knowledge with updated information from recent years. It serves as a guide for academic and professional researchers and clinicians.

Amazon Web Services: A Comprehensive Guide for Beginners and Advanced Users is your go-to companion for learning and mastering AWS. It presents 10 easy-to-read chapters that build a foundation for cloud computing while also equipping readers with the skills necessary to use AWS for commercial projects. Readers will learn how to use AWS cloud computing services for seamless integrations, effective monitoring, and optimizing cloud-based web applications.

What you will learn from this guide:

1. Identity and Access Management in AWS: Learn about IAM roles, security of the root account, and password policies, ensuring a robust foundation in access management.

2. Amazon EC2 Instance: Explore the different types of EC2 instances, pricing strategies, and hands-on experiences to launch, manage, and terminate EC2 instances effectively. This knowledge will help to make informed choices about pricing strategies.

3. Storage Options and Solutions: A detailed examination of storage options within Amazon EC2 instances. Understanding Amazon Elastic Block Store (EBS), Amazon Elastic File Storage (EFS), and more, will enhance your ability to handle data storage efficiently.

4. Load Balancing and Auto Scaling: Learn about different types of load balancers and how auto-scaling groups operate, to master the art of managing varying workloads effectively.

5. Amazon Simple Storage Service (S3): Understand S3 concepts such as buckets, objects, versioning, storage classes, and practical applications.

6. AWS Databases and Analytics: Gain insights into modern databases, AWS cloud databases, and analytics services such as Amazon Quicksight, AWS Glue, and Amazon Redshift.

7. Compute Services and Integrations: Understand the workings of Docker, virtual machines, and various compute services offered by AWS, including AWS Lambda and Amazon Lightsail, Amazon MQ and Amazon SQS.

8. Cloud Monitoring: Understand how to set up alarms, analyze metrics, and ensure the efficient monitoring of your cloud environment using Amazon CloudWatch and CloudTrail.

Key Features: Comprehensive Introduction to Cloud Computing and AWS Guides readers to the complete set of features in AWS Easy-to-understand language and presentation with diagrams and navigation guides References for further reading Whether you're a student diving into cloud specialization as part of your academic curriculum or a professional seeking to enhance your skills, this guide provides a solid foundation for learning the potential of the AWS suite of applications to deploy cloud computing projects.

The second law of thermodynamics is an example of the fundamental laws that govern our universe and is relevant to every branch of science exploring the physical world. This reference summarizes knowledge and concepts about the second law of thermodynamics and entropy. A verbatim explanation of chemical thermodynamics is presented by the author, making this text easy to understand for chemistry students, researchers, non-experts, and educators.

This e-book adds a new dimension to currently available text in health promotion by applying examples from evaluation studies to explore basic health promotion principles. It thus goes beyond single case study descriptions. The volume intricately blends an ecological approach with social science.

A multiple settings approach is extensively covered by analyzing participants’ perceptions of the family, leisure and school settings. Chapters of this volume also present intervention data aiming at promoting participants’ perceptions and empowerment in the settings. Furthermore, the e-book covers several topic areas central to health promotion, such as life satisfaction, health behaviours (tobacco, physical activity) and health complaints and body image. Another central principle in health promotion, namely development of healthy public policy is covered including descriptions about how health promotion policies are influenced by national and international political developments. This historical perspective adds to the current knowledge of how to establish and develop policies as a basis for all health promotion actions.

The Abu Serga Church is one of the oldest known Coptic churches in Egypt, with a history of almost 1700 years. This reference work presents a comprehensive geotechnical and geophysical survey of the vicinity of the Abu Serga Church. The book details the information of the survey using classical and modern methods of geotechnical engineering while keeping contemporary issues faced by site investigators in view. Chapters provide the data of the church site while covering topics of interest to students such as seismic analysis, 3-D modeling and historical preservation principles. Advanced methods of interest to engineers such as mathematical analysis using finite element methods are also covered.

This work provides key data about the Abu Sega Church site and is of interest to scholars and engineers involved in conservation engineering of architectural heritage (or built heritage), as well as readers interested in church studies.

The kidneys are a vital organ present in humans and vertebrate animals. Various toxic chemicals, present in food and water adversely affect the kidneys. Plants and plant-derived compounds have been a major source for the treatment and cure of diseases since ancient times. Even today, almost 25% of the prescription drugs for renal problems are sourced from plants. An Introduction to Nephroprotective Plants gives an overview of nephrotoxicity and medicinal plants used for protecting the kidney and reducing the effect of kidney toxicity and managing renal diseases. This book is an answer to the current gaps in knowledge resources on nephroprotective plants. The reader is introduced to the basic physiology of the renal excretory system and its disorders. The introduction is followed by chapters which give information on medicinal plants used in traditional systems of medicine (both codified and noncodified). Information about plant parts used, method of use and dosage is provided along with references.

Key Features:

- Simple structured presentation in six chapters

- Includes an introduction to the urinary system and its diseases

- Includes information about codified and noncodified medicinal plants used for neuroprotection

- Covers phytochemicals extracted from medicinal plants which are screened and used in modern medicine for nephroprotection in detail.

- Covers ethnobotanical and polyherbal formulations

- References for further reading

An Introduction to Nephroprotective Plants serves as a convenient desk reference for all researchers (pharmacologists, medicinal chemists, ethnobotanists) and healthcare professionals (physicians, pharmacists, nurses and medical students) who require complete information on nephroprotective plants.

This book represents a novel approach for the trigonometry and an original scientific work in this field, by using the ensemble structure composed of the real analysis and the axiomatic fundaments of geometry. Throughout this e – book one presents, in a proper manner, definitions, properties, formulae and applications more specific of the subject title and its immediate connections. The book is recommended not only as a pertinent introduction for the high school students, being also very useful for the university students, mathematics teachers and anyone who is interested in the major elements regarding the essence of real mathematics.

This e-book provides several state-of-the-art analog circuit design techniques. It presents both empirical and theoretical materials for system-on-a-chip (SOC) circuit design. Fundamental communication concepts are used to explain a variety of topics including data conversion (ADC, DAC, Σ-Δ oversampling data converters), clock data recovery, phase-locked loops for system timing synthesis, supply voltage regulation, power amplifier design, and mixer design. This is an excellent reference book for both circuit designers and researchers who are interested in the field of design of analog communication circuits for SOC applications.

Analysis of Boundedness and Safeness in a Petri Net-Based Specification of Concurrent Control Systems provides a comprehensive study of concurrent control systems using Petri net models, with a focus on boundedness and safeness analysis. Designed for both academic and industry professionals, it bridges the gap between theoretical rigor and practical applications, offering essential insights for advancing knowledge in the field.

The content covers foundational principles of control systems and Petri nets before exploring advanced analysis techniques. Topics include algorithms, computational complexity, and different Petri net classes. The book also addresses boundedness and safeness properties, presenting verification methods, case studies, and experimental results. Trends, challenges, and future directions are also discussed in the book equipping readers with practical tools to innovate in concurrent system design.

Key Features:

- In-depth coverage of Petri net-based concurrent system modeling and analysis.

- Clear explanations supported by real-world examples and case studies.

- A balanced approach combining theory and application.

Anatomy for Oral and Maxillofacial Radiology is a handy atlas for medical students and residents learning about radiography and diagnostic procedures in oral and maxillofacial medicine. This brief book starts from basic information about radiographic images and expands into chapters detailing intraoral diagnostic techniques, extraoral diagnostic techniques and oral/maxillofacial abnormalities. Over 80 illustrations demonstrate key concepts in radiography. The reader will gain a good understanding of oral and maxillofacial diagnosis which is required for basic clinical practice in the specialty.

Anatomy: A Pressing Concern in Exercise Physiology is a thorough analysis of the importance of anatomy in exercise physiology courses. It presents a series of topics that cover key concept and terms in anatomy, muscle physiology, kinesiology, the use of imagery in anatomy, physical flexibility and the conventional study of cadavers. Readers of the book will receive reliable anatomical knowledge, well-researched cadaver information as well as information about good, useless, and dangerous exercises. Readers will essentially be equipped to supervise exercise training designed to be safe while providing a greater range of physical motion.

Anatomy: A Pressing Concern in Exercise Physiology serves as a textbook for exercise physiologists in training and as a handbook for healthcare professionals involved in the physical training or rehabilitation of clients or patients.

Individuals with Angelman Syndrome (AS) present many unique challenges to professionals, parents and others who are committed to maximizing individuals’ competence while ensuring them the best possible quality of life. Angelman Syndrome: Communication, Educational, and Related Considerations is a unique, exhaustive compilation of existing material related to understanding the nature of AS and how individuals’ communication and related skills can be fostered most effectively. It provides readers with a comprehensive understanding of the background of Angelman Syndrome along with an in-depth exploration of communication (with a focus on augmentative and alternative communication), educational, and related issues that should be addressed when attempting to meet the needs of individuals with AS at home, school, work, and elsewhere in the community.

Key features of the book include:

• Extensive background information about medical and related factors behind AS and how they influence individuals’ learning

• A series of prologues written by the parents of individuals with AS

• Contributions from internationally recognized experts on AS, communication disorders, psychology and education

• Numerous practical, evidence-based strategies for conducting assessments and carrying out interventions among AS affected individuals

Speech-language pathologists, allied healthcare providers and educators providing support to affected individuals should benefit from the information provided in the book by being able to identify appropriate communication, behavioral and educational goals. Laypersons, particularly parents, will also find the information highly useful in advocating for best practices for their children (which is partly fostered by the series of parental prologues).

Angelman Syndrome: Communication, Educational, and Related Considerations will not only serve as a valuable reference for improving the learning experience for AS affected individuals but will also embolden both professionals and parents to maintain higher expectations for them.

This reference presents information about models utilized in experimental medicine and pharmaceutical research and development for several human diseases. Written by experts in immunology, cancer biology and pharmacology, the book provides readers with handy notes and updated data on animal models that are critical to research planning and lab execution.

The main feature of the book is a set of 12 structured chapters that focus on a specific disease such as cancer, infectious diseases, autism, autoimmune diseases, Alzheimer's disease and anemia. The contributors have gathered information on a wide range of genetic and physiological animal models that are employed in research with comparative charts that highlight their main differences. The book also includes chapters for special topics like food allergies and dentistry. Additional features of the book are an explanation of disease mechanisms that give an easy understanding, notes for idiopathic models and specific clinical conditions, and a list of references for advanced readers.

Animal Models In Experimental Medicine is essential reading for scholars, graduate students and senior researchers in life sciences and clinical medicine. It also serves as a resource for professionals involved in bench-to-bedside pharmaceutical projects.

Anthocyanins are a diverse group of phytochemicals used for the treatment and management of acute and chronic ailments. This book is a comprehensive guide to anthocyanins and their importance as pharmaceutical and nutraceutical agents. The book provides detailed information about anthocyanin sources and their application in the treatment of diseases including cancer, gastric disorders, infertility, metabolic diseases, and neurological disorders.

Key features

· Explains the importance of phytochemicals and nutraceuticals

· Provides details of anthocyanin sources and mechanisms of action

· Includes chapters dedicated to the use of anthocyanins to treat specific diseases

· Provides a summary of the market for anthocyanins as a pharmaceutical and nutraceutical product

· Includes scientific references

Following the post 9/11 distribution of anthrax spores through the U.S. mail, and the resulting deaths of five individuals - primarily due to initial misdiagnosis - there has been a renewed interest in anthrax among clinicians and intelligence agencies, particularly as a biological warfare agent. This monograph brings forth essential knowledge about anthrax. Included in this volume, are, the early history, non-natural outbreaks of anthrax, characteristics of the causative organism Bacillus anthracis and its relationship to other members of the B. cereus family. Also included are reports on extensive clinical findings, mechanisms of anthrax virulence and the genetics responsible for these virulence factors. The extensive studies over the years regarding the development of veterinary and human vaccines, and molecular studies, including conventional PCR and real-time PCR are explained in comprehensive detail, with the help of tables, figures and extensive references. This eBook serves as an advanced presentation and reference work for individuals seeking detailed information regarding anthrax and as a primary guide for individuals pursuing studies on anthrax.

The inhibition of angiogenesis is an effective mechanism of slowing down tumor growth and malignancies. The process of induction or pro-angiogenesis is highly desirable for the treatment of cardiovascular diseases, wound healing disorders, etc. Efforts to understand the molecular basis, both for inhibition and induction, have yielded fascinating results.

Anti-angiogenesis Drug Discovery and Development provides is an excellent compilation of well-written reviews on various aspects of the anti-angiogenesis process. These reviews have been contributed by leading practitioners in drug discovery science and highlight the major developments in this exciting field in the last two recent decades. The feast of these reader-friendly reviews on topics of great scientific importance – many of which are considered significant medical breakthroughs, makes this book excellent reading both for the novice as well as for expert medicinal chemists and clinicians.

The second volume of this ebook series covers topics including:

-Clear Cell Renal Cell Carcinoma as a Model of Pathological Angiogenesis

-Discovery and Development of Antiangiogenetic Drugs in Ovarian Cancer

-Anti-Angiogenic Therapy and Cardiovascular Diseases

… and more.

The inhibition of angiogenesis is an effective mechanism of slowing down tumor growth and malignancies. The process of induction or pro-angiogenesis is highly desirable for the treatment of cardiovascular diseases, wound healing disorders, etc. Efforts to understand the molecular basis, both for inhibition and induction, have yielded fascinating results.

Anti-angiogenesis Drug Discovery and Development provides an excellent compilation of well-written reviews on various aspects of the anti-angiogenesis process. These reviews have been contributed by leading practitioners in drug discovery science and highlight the major developments in this exciting field in the last two decades. The feast of these reader-friendly reviews on topics of great scientific importance – many of which are considered significant medical breakthroughs, makes this series excellent reading both for the novice as well as for expert medicinal chemists and clinicians.

This volume brings together 5 reviews on the following topics:

- Retinal angiogenesis

- Effects of brief daily EMF therapy on tumor growths

- Evolution of the role of angiogenesis in cancer treatments over six decades

- Anti-angiogenesis drugs

- Anti-angiogenesis therapy for multiple sclerosis

- Update on the link between angiogenesis and portal hypertension

Obesity is a complex health problem, caused by a number of factors such as excessive food intake, lack of physical activity, genetic predisposition, endocrine disorders, medications and psychiatric illnesses. Onset of obesity in both the developing and the developed world has reached epidemic proportions. In response to this, efforts to control and treat obesity have also been vigorously pursued, ranging from raising awareness about lifestyle changes to the discovery and development of safe and effective anti-obesity drugs.

Anti-obesity Drug Discovery and Development is focused on this very important area of healthcare research. Fifteen well written reviews make this special volume an excellent compilation of recent developments in anti-obesity treatment. The reviews cover a variety of topics including the development of specific, safe and effective receptor antagonists, the role of epithelial endocrine cells and post operative treatment strategies. This book should be useful to clinicians and medicinal chemists involved in ant-obesity research and therapy.

Obesity is a complex health problem, caused by a number of factors such as excessive food intake, lack of physical activity, genetic predisposition, endocrine disorders, medications and psychiatric illnesses. Onset of obesity in both the developing and the developed world has reached epidemic proportions. In response to this, efforts to control and treat obesity have also been vigorously pursued, ranging from raising awareness about lifestyle changes to the discovery and development of safe and effective anti-obesity drugs.

Anti-obesity Drug Discovery and Development is focused on this very important area of healthcare research. The third volume of this series is dedicated to anti-obesity treatments including updates on new therapeutics for obesity, Nesfatin-1 and its therapeutic uses, the role of proteomics in pediatric anti-obesity treatment, the role of oxidative stress in childhood obesity and a review of data on gut microbiota as a treatment option for obesity.

Obesity is a complex health problem, caused by a number of factors such as excessive food intake, lack of physical activity, genetic predisposition, endocrine disorders, medications and psychiatric illnesses. The incidence of obesity among populations in both the developing and the developed world has reached epidemic proportions. In response to this, efforts to control and treat obesity have also been vigorously pursued, ranging from activities focused on raising awareness about lifestyle changes to the discovery and development of safe and effective anti-obesity drugs. Anti-obesity Drug Discovery and Development is a book series focused on this very important area of healthcare research. Each volume presents insightful updates on pharmaceutical research and development for clinical researchers and healthcare professionals involved in obesity treatment programs.

The fifth volume of this series is a compilation of 6 reviews of interesting topics on the subject that highlight different aspects of obesity treatment and management, some of which are novel approaches. Topics covered in this volume include:

- the effect of sleep on weight and obesity management

- AMPK as a postulated target for metabolic syndrome and obesity

- Harnessing addiction neuroscience to treat obesity

- Current treatment of obesity versus the next generation of anti-obesogenic drugs: an ecologically and sustainable approach to health

- Leptin and leptin sensitizers for the treatment of obesity related conditions

- MicroRNAs as targets for the management of obesity

This handbook focuses on the use of antibiotic alternatives in poultry and fish feed. Chapters in the book cover a range of natural ingredients in feed and the impacts of these natural feed additives on growth, production, reproduction and health status of poultry and fish. All chapters give a holistic approach to how organic feed additives (herbal plants and their extracts, probiotics, peptides, etc.) can positively impact animal health and production.

Key Features:

- presents 13 chapters contributed by 38 experts and scientists of animal, poultry and fish nutrition, poultry and fish physiology, toxicology, pharmacology, and pathology

- highlights the significance of herbal plants and their extracts and derivatives, cold-pressed and essential oils and fruits by-products

- covers the effects of special ingredients such as immunomodulators, antimicrobial peptides, and probiotics

- provides the reader an updated perspective on the use of additives in poultry and fish industry as growth promoters and their role in developing bacterial resistance to antibiotics

- covers the main poultry species, egg-laying hens, quails, geese, ducks, turkey, and commercial fish

- includes references for advanced readers

This book will be useful for poultry and fish keepers and researchers in animal nutrition, pharmacology, and veterinary sciences. Professionals involved in the poultry and fish feed industry will also find the information useful for product development.

Antibodies Applications and New Developments is an overview of the current developments of techniques and methods relating to immunodiagnostics and immunoanalysis. This eBook also deals with specialties in the fields of drug, pesticide, antigen and food contaminant detection. The volume is useful for professional immunologists and biotechnologists interested in antibody research and development.

Probiotics have been suggested to be involved in both prevention and treatment of various human cancers. Anticancer Immunity: Reviewing the Potential of Probiotics explains biochemical mechanisms of anticancer immunity exerted by probiotics in various human cancers. It presents edited chapters focused on the evidence of probiotic use against human cancers through several animal and human studies. This volume consists of 11 chapters. The volume continues from the previous entry with chapters focused on probiotics' anticancer immunity in specific cancers such as, bladder cancer, renal cell carcinoma, prostate cancer, lymphomas, pancreatic cancer, oral cancer and oropharyngeal cancers. The book concludes with chapters that inform readers about the value of prebiotics, postbiotics and postbiotics in cancer therapy as adjuvants and immunotherapeutic agents. Key features - Gives a new dimension and insight in the role of probiotics in anticancer immunity towards various human cancers - Provides several color figures and tables to clearly explain relevant information. - Includes recent information with new insights and references - Meets the needs of basic (pre-clinical) and advanced clinical researchers and postgraduate scholars

The book covers the applications of some alternative approaches for prolonging food shelf life. The book describes the role of food safety objectives, natural compounds (such as oils and microbial enzymes), pressure and atmospheric techniques and alternative approaches (microwave, irradiation and mathematical microbial modeling) in food preservation.

Implications of preservative approaches on food texture and sensorial quality are also discussed along with technology related hurdles commonly encountered in the field. The book should be very useful for food producers and microbiologists.

This book provides a thorough investigation of the application of chaos theory and fractal analysis to computer vision. The field of chaos theory has been studied in dynamical physical systems, and has been very successful in providing computational models for very complex problems ranging from weather systems to neural pathway signal propagation. Computer vision researchers have derived motivation for their algorithms from biology and physics for many years as witnessed by the optical flow algorithm, the oscillator model underlying graphical cuts and of course neural networks. These algorithms are very helpful for a broad range of computer vision problems like motion segmentation, texture analysis and change detection.

The contents of this book include chapters in biological vision systems, foundations of chaos and fractals, behavior of images and image sequences in phase space, mathematical measures for analyzing phase space, applications to pre-attentive vision and applications to post-attentive vision.

This book is intended for graduate students, upper division undergraduates, researchers and practitioners in image processing and computer vision. The readers will develop a solid understanding of the concepts of chaos theory and their application to computer vision. Readers will be introduced to a new way of thinking about computer vision problems from the perspective of complex dynamical systems. This new approach will provide them a deeper understanding of the various phenomena present in complex image scenes.

This book is a guide to the application of ionic liquids (ILs) in the oil industry. It includes ten chapters that review basic and advanced topics. Starting with a general introduction to IL structure and properties, the book comprehensively explains the use of ILs in key petroleum extraction processes such as pollutant removal, demulsification, crude oil transport and oil recovery. Additional applications that are important for the sustainability management of petrochemical operations such as deepwell hydrate inhibition, CO2 capture, corrosion engineering, catalysis, hydrocarbon separation, bitumen extraction and stabilization are also included. Each chapter also provides bibliographic references for further reading. The wide range of topics makes this an informative reference to students and professionals in petroleum engineering, chemical engineering programs and any other training course that requires reading material for an understanding of the oil industry. General readers and researchers interested in the fascinating chemistry of ionic liquids will also enjoy this book.

Applications of Modern Mass Spectrometry, Volume 2, covers the latest advances in mass spectrometry in scientific research. The series presents readers with information on the broad range of mass spectrometry techniques and configurations, data analysis, and practical applications. Each volume contains contributions from eminent researchers who present their findings in an easy-to-read format. The multidisciplinary nature of the works presented in each volume of this book series makes it a valuable reference on mass spectrometry to academic researchers and industrial R&D specialists in applied sciences, biochemistry, life sciences, and allied fields.

The second volume of the series presents 6 reviews: Ion Mobility-Mass Spectrometry for Macromolecule Analysis - Recent Advancements in Detection of Organic Contaminants in Wastewater Using Advanced Mass Spectrometry - Poisonous Substances in Tropical Medicinal and Edible Plants: Traditional Uses, Toxicology, and Characterization by Hyphenated Mass Spectrometry Techniques - LC-MS Analysis of Endogenous Neuropeptides from Tissues of Central Nervous System: An Overview - Advances in Structural Proteomics Using Mass Spectrometry and Recent Trends of Modern Mass Spectrometry: Application towards Drug Discovery and Development Process.

Applications of NMR Spectroscopy is an eBook series devoted to publishing the latest advances in the application of nuclear magnetic resonance (NMR) spectroscopy in practical situations. The second volume of this eBook series features five chapters covering NMR spectroscopic analysis of plant polyphenols, the role of NMR spectroscopy in neuroradiology, NMR –based sensors, studies on protein and nucleic acid structure and function, and mathematical formations for NMR spectroscopy in structural biology.

Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture.

The fourth volume of the series features several reviews focusing on NMR spectroscopic techniques in food sciences. Readers will find references on methods used to test food quality, food color analysis, the role of Tannins in wine taste as well as NMR studies on lipid oxidation and large protein complexes.

Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture.

The sixth volume of the series features reviews focusing on NMR spectroscopic techniques for studying tautomerism, applications in medical diagnosis, in food chemistry and identifying secondary metabolites.

Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture.

The eighth volume of the series features six reviews focusing on NMR spectroscopic techniques in food science, molecular biology and medical diagnosis. The reviews in this volume are:

- qNMR as a Tool for Determination of Six Common Sugars in Foods

- Correlation of VIP Scores and 1H NMR to Extract Information of Psychological Attention Tests Applied Before and After Coffee Intake

- NMR Spectroscopy for Probing the Structural Determinants of Aptamer Optimization and Riboswitch Engineering

- Applications of NMR Spectroscopy in Medical Diagnosis

- Applications of NMR Spectroscopy in Cancer Diagnosis

- NMR as a Tool for Exploring Protein Interactions and Dynamics

This volume describes recent advancements in the synthesis and applications of nanomaterials for energy harvesting and storage, and optoelectronics technology for next-generation devices.

This book consists of 15 chapters that cover a range of nanomaterials and the corresponding technologies.

The initial chapters summarize the recent progress in applications of nanomaterials like carbon nanotubes, metal oxides, and graphene oxides-based hybrids in solar energy harvesting using recent photovoltaic technologies. These chapters are followed by reviews on nanowires, graphene quantum dots, boron nitrides, carbon nano onions and metal organic frameworks leading to the fabrication of supercapacitors, bio-sensors, lithium-ion batteries and hydrogen storage applications. The final set of chapters cover the next generation fuel cells using polymer nanocomposites, ferroelectric liquid crystal nanocomposite and optoelectronic nanomaterials for optical memory and displays devices.

Key Features:

Describes the types of nanomaterials that are fundamental to energy storage and electronic systems. These materials include nanowires, graphene quantum dots, boron nitrides, carbon nano onions and metal organic frameworks (MOFs),

Covers the processes for nanomaterial synthesis

Reviews important photovoltaics applications of nanomaterials, including their use in energy storage, batteries and optoelectronic devices

Discusses the application of nanomaterials in electronics for sensing, bioelectronics, memory, nanocomposites for fuel cells, ferroelectric liquid crystal nanocomposites and optoelectronic nanomaterials for optical memory and displays

Provides references for further reading in every chapter The volume informs engineers, academic researchers, research scholars and graduate students working in the area of nanomaterials for energy generation, storage and optoelectronics.

Applications of Nanoparticles in Drug Delivery and Therapeutics is an authoritative review on nanoparticle-based drug delivery systems. This comprehensive volume focuses on the transformative role of nanoparticles in enhancing drug delivery systems and advancing therapeutic applications. By bridging the gap between laboratory research and clinical practice, this book offers a thorough exploration of how nanotechnology is revolutionizing the pharmaceutical industry.

The book is structured into well-organized chapters, each dedicated to a specific aspect of nanoparticle-based drug delivery and therapy. Initial chapters provide a foundational understanding of nanoparticle synthesis, characterization, and functionalization. Subsequent sections cover various types of nanoparticles, including liposomes, dendrimers, and polymeric nanoparticles, highlighting their unique properties and applications. The latter chapters delve into case studies and clinical trials, showcasing real-world applications and the therapeutic potential of nanoparticle technologies in treating diseases like cancer, cardiovascular disorders, and neurodegenerative diseases.

Key features of this book include detailed discussions on the design and optimization of nanoparticles for targeted drug delivery, insights into the regulatory and safety aspects of nanomedicine, and comprehensive reviews of current and emerging therapeutic applications. The book also offers practical guidance on the challenges and future directions in the field, making it an invaluable reference for researchers and practitioners alike.

Chapters 1 and 2 are based on the introduction of nanomaterials used as drug delivery systems, their manufacturing approaches and applications. Chapters 3 and 4 emphasize on the use of nanoparticles in medical diagnostics and in intervention devices. Chapters 5 and 6 illustrate the use of lipids-based nanoparticles in medical imaging and drug delivery. Chapter 7 specifically discusses amino acid functionalized inorganic nanoparticles in diagnostics. Chapter 8 is focused on the special class of nanoparticles “hybrid nanocomposites”. Chapters 9 and 10 covers the applications of silica and fullerene nanomaterials in anticancer drug delivery.

The book is intended as a resource for pharmaceutical scientists, biomedical researchers, and healthcare professionals keen on the latest advancements in drug delivery systems. It also serves as essential reading for graduate students and academics in pharmacology and medical courses that require learning about modern drug delivery systems.

The chemistry of heterocomplex compounds is a fascinating field for experts in chemical synthesis and structural analysis, and for technologists specializing in leather processing. This volume describes the vast theoretical and practical possibilities of exploiting the action synergism of metals with different collagen cross-linking capacity. The possibility of reducing chromium content from leather tanning agents by replacing it with other tanning metals has significant environmental implications and minimum changes in terms of quality and production costs of natural leather, and is a viable alternative for a safe future. Applicative Chemistry of Tanning Metallic Heterocomplexes is a book dedicated to the synthesis and use of tanning metallic heterocomplexes in leather tanning as alternatives to tanning with basic chromium salts. Replacing chromium with other tanning metals is an innovative approach that exploits the possibility that a series of known disadvantages of tanning metals used individually be reduced by heterocomplexation. The synthesis mechanism of stable combinations of chromium with other tanning metals: aluminum, iron, titanium, or zirconium is based on the stoichiometry of oxidation-reduction reactions which enables a wide range of combinations, the premise for obtaining various properties by tanning and retanning natural leather. The volume is intended as a useful reference for researchers, chemical auxiliary producers, experts in natural leather processing who are looking for clean and efficient solutions for wastewater pollutants, sludge or solid wastes while striving to preserve the known characteristics of mineral tanned natural leather.